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  4. Recombinant Mouse Transcription cofactor vestigial-like protein 2 (Vgll2)

Recombinant Mouse Transcription cofactor vestigial-like protein 2 (Vgll2)

  • 中文名称：
    小鼠Vgll2重组蛋白
  • 货号：
    CSB-YP805882MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Vgll2重组蛋白
  • 货号：
    CSB-EP805882MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Vgll2重组蛋白
  • 货号：
    CSB-EP805882MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Vgll2重组蛋白
  • 货号：
    CSB-BP805882MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Vgll2重组蛋白
  • 货号：
    CSB-MP805882MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Vgll2
  • Uniprot No.：
  • 别名：
    Vgll2; Vgl2; Vito1Transcription cofactor vestigial-like protein 2; Vgl-2; Protein VITO1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-322
  • 氨基酸序列
    MSCLDVMYQV YGPPQPYFAA AYTPYHQKLA YYSKMQEAQE CASPGSSASG SSSFSNPTPA SVKEEEGSPE KERPPEAEYI NSRCVLFTYF QGDISSVVDE HFSRALSHPS SYTPSCTSSK AHRSSGPWRA EGTFPMSQRS FPASFWNSAY QAPVPAPLGS PLAAAHSELP FATDPYSPAT LHGHLHQGAA DWHHAHPHHA HPHHPYALGG ALGAQASAYP RPAVHEVYAP HFDPRYGPLL MPAATGRPGR LAPASAPAPG SPPCELAAKG EPAGSAWAAP GGPFVSPTGD VAQSLGLSVD SGKRRRECSL PSAPPALYPT LG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.
  • 基因功能参考文献：
    1. VITO-1 is a crucial new cofactor of the muscle regulatory programme; VITO-1, a new scalloped interaction domain-containing protein, binds to TEF1 in vitro and strongly stimulates transcription of a reporter plasmid together with TEF-1 PMID: 14762206
    2. Vestigial like 2 homolog is required for muscle gene expression, in part by switching DNA binding of TEF-1 factors during muscle differentiation. PMID: 15287000
    3. A transcription cofactor required for skeletal muscle differentiation that modifies DNA target selectivity of the Transcriptional Enhancer Factor-1 (TEF-1) transcription factors. PMID: 15287000
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Vestigial family
  • 组织特异性：
    Skeletal muscle specific.
  • 数据库链接：

    KEGG: mmu:215031

    STRING: 10090.ENSMUSP00000124091

    UniGene: Mm.87237