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  4. Recombinant Mouse Thioredoxin reductase 3 (Txnrd3)

Recombinant Mouse Thioredoxin reductase 3 (Txnrd3)

  • 货号：
    CSB-YP025390MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP025390MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP025390MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP025390MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP025390MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Txnrd3
  • Uniprot No.：
  • 别名：
    Txnrd3; Tgr; Trxr3; Thioredoxin reductase 3; EC 1.8.1.9; Thioredoxin and glutathione reductase; Thioredoxin reductase TR2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-652
  • 氨基酸序列
    MEKPPSPPPP PRAQTSPGLG KVGVLPNRRL GAVRGGLMSS PPGRRARLAS PGTSRPSSEA REELRRRLRD LIEGNRVMIF SKSYCPHSTR VKELFSSLGV VYNILELDQV DDGASVQEVL TEISNQKTVP NIFVNKVHVG GCDRTFQAHQ NGLLQKLLQD DSAHDYDLII IGGGSGGLSC AKEAANLGKK VMVLDFVVPS PQGTTWGLGG TCVNVGCIPK KLMHQAALLG HALQDAKKYG WEYNQQVKHN WEAMTEAIQS HIGSLNWGYR VTLREKGVTY VNSFGEFVDL HKIKATNKKG QETFYTASKF VIATGERPRY LGIQGDKEYC ITSDDLFSLP YCPGCTLVVG ASYVGLECAG FLAGLGLDVT VMVRSVLLRG FDQEMAEKVG SYLEQQGVKF QRKFTPILVQ QLEKGLPGKL KVVAKSTEGP ETVEGIYNTV LLAIGRDSCT RKIGLEKIGV KINEKNGKIP VNDVEQTNVP HVYAIGDILD GKPELTPVAI QAGKLLARRL FGVSLEKCDY INIPTTVFTP LEYGCCGLSE EKAIEMYKKE NLEVYHTLFW PLEWTVAGRD NNTCYAKIIC NKFDNERVVG FHLLGPNAGE ITQGFAAAMK CGLTKQLLDD TIGIHPTCGE VFTTLEITKS SGLDITQKGC UG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
  • 基因功能参考文献：
    1. Study shows that CUG codon is used as an inefficient start codon to generate protein Thioredoxin/glutathione reductase isoforms in mouse. PMID: 20018845
  • 亚细胞定位：
    Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum.
  • 蛋白家族：
    Class-I pyridine nucleotide-disulfide oxidoreductase family
  • 组织特异性：
    Expressed preferentially in testis where it is found in spermatids and spermatocytes but not in sperm. In elongating spermatids, expressed at the site of mitochondrial sheath formation. Low levels in other tissues including heart, lung, liver, kidney, bra
  • 数据库链接：

    KEGG: mmu:232223

    STRING: 10090.ENSMUSP00000000828

    UniGene: Mm.229332