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  4. Recombinant Mouse Thioesterase superfamily member 4 (Them4)

Recombinant Mouse Thioesterase superfamily member 4 (Them4)

  • 货号：
    CSB-YP023494MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP023494MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP023494MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP023494MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP023494MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Them4; Ctmp; Acyl-coenzyme A thioesterase THEM4; Acyl-CoA thioesterase THEM4; EC 3.1.2.2; Carboxyl-terminal modulator protein; Thioesterase superfamily member 4
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    28-230
  • 氨基酸序列
    SSE KVIRKDYALP NPSWTKDLRL LFDQFMKKCE DGSWKRMPSH RQNPTRAIQE FQTLFVDSKF KKEEQMSKAQ QFTRSFEEGL GFEYAMFYNK VEKRTVSLFQ GGLHLQGVPG FVHGGAIATI IDVTTGTCAI SEGVAMTANL NITYKKPIPL LSVVVVNSQL QKIEGRKLFV SCTIQSIDEK TLYTEATALF IKLDPEKPLT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity.
  • 基因功能参考文献：
    1. Results suggest that Akt is phosphorylated and translocated to nucleus after traumatic brain injury (TBI) to exert neuroprotective effects; however, CTMP is simultaneously triggered to inhibit the phosphorylation of Akt PMID: 24670215
  • 亚细胞定位：
    Cell membrane. Cell projection, ruffle membrane. Cytoplasm. Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
  • 蛋白家族：
    THEM4/THEM5 thioesterase family
  • 数据库链接：

    KEGG: mmu:75778

    STRING: 10090.ENSMUSP00000062841

    UniGene: Mm.45092