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  4. Recombinant Mouse Testis-expressed sequence 101 protein (Tex101)

Recombinant Mouse Testis-expressed sequence 101 protein (Tex101)

  • 中文名称：
    小鼠Tex101重组蛋白
  • 货号：
    CSB-YP864380MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Tex101重组蛋白
  • 货号：
    CSB-EP864380MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tex101重组蛋白
  • 货号：
    CSB-EP864380MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tex101重组蛋白
  • 货号：
    CSB-BP864380MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tex101重组蛋白
  • 货号：
    CSB-MP864380MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Tex101
  • Uniprot No.：
  • 别名：
    Tex101; Testis-expressed protein 101; TES101-reactive protein; TES101RP
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-224
  • 氨基酸序列
    TYCQV SQTLSLEDDP GRTFNWTSKA EQCNPGELCQ ETVLLIKADG TRTVVLASKS CVSQGGEAVT FIQYTAPPGL VAISYSNYCN DSLCNNKDSL ASVWRVPETT ATSNMSGTRH CPTCVALGSC SSAPSMPCAN GTTQCYQGRL EFSGGGMDAT VQVKGCTTTI GCRLMAMIDS VGPMTVKETC SYQSFLQPRK AEIG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct probably through molecule adhesion ADAM3. May play a role in signal transduction and promote protein tyrosine phosphorylation.
  • 基因功能参考文献：
    1. Study demonstrated that both TEX101 and Ly6k contribute mutually for their protein expression in the testicular germ cells, suggesting that the expression-balance of these two proteins is essential for fertile sperm formation. PMID: 27005865
    2. Tex101 knockout sperm lost the adhesive ability to the surface of female genital tract. PMID: 23969891
    3. TEX101 is a unique specific substrate for ACE that is essential for the production of fertile mouse spermatozoa PMID: 23633567
    4. NYD-SP8 has a role in regulating ECM degradation, providing a novel mechanism that modulates urokinase signalling in the suppression of cancer progression PMID: 19017363
    5. DPEP3 forms complexes with Ts4-immunoreactive molecules, such as TEX101, on the surfaces of spermatocytes, spermatids, and testicular spermatozoa. PMID: 21724266
    6. may play an important physiological role in germ cell development PMID: 15689535
    7. Deletion analysis of the chimeric structures indicated that sequences essential to gene expression should facilitate an understanding of the regulation of TEX101 expression during gametogenesis. PMID: 16941676
    8. This study confirmed the biological interaction between TEX101 and Ly6k. PMID: 18503752

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted. Cytoplasmic vesicle.
  • 组织特异性：
    Detected in testis and ovary. Expressed in spermatocytes, spermatids and testicular spermatozoa, but not in spermatogonia or interstitial cells. Expressed abundantly in testicular germ cells (TGCs) but mostly disappeared from epididymal spermatozoa.
  • 数据库链接：

    KEGG: mmu:56746

    STRING: 10090.ENSMUSP00000077150

    UniGene: Mm.23385