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  4. Recombinant Mouse Spermatogenesis-defective protein 39 homolog (Spe39)

Recombinant Mouse Spermatogenesis-defective protein 39 homolog (Spe39)

  • 货号：
    CSB-YP805253MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP805253MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP805253MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP805253MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP805253MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Vipas39
  • Uniprot No.：
  • 别名：
    Vipas39; Spe39; Vipar; Spermatogenesis-defective protein 39 homolog; hSPE-39; VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein in polarity and apical restriction
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-491
  • 氨基酸序列
    MNRTKGDEEE YWNSSKFKAF TFDDEDDELS QLKESKRAVN SLRDIVDDDD DDDLERVSWT GEPVGSISWS IKETAGSSGS TPEGREQLKG RNSFYTQLPK PPSTYSLSSF FRGRTRPGSF QSLSDALSDT PAKSYAPELG RPKGEYRDYS NDWSLSDTVQ RLRRGKVCSL ERFRSLQDKL QLLEEAVSMH DGNVITAVLI FLKRTLSKEI LFRELEVRQV ALRHLIHFLK EIGDQKLLLD LFRFLDRAEE LALSHYREHL NIQDPEKRKE FLKTCIGLPF SAEDAAHVQD HYTLLERQII IEANDRHLES SGQTDIFRKH PRKASILNMP LVTTLFYACF YHYTESEGTF SSPINLKKTF KIPDKQYVLT ALAARAKLRA WNDVDALFTT KNWLGYTKKR APIGFHRVVE ILHKNSAPVQ ILQEYVNLVE DVDTKLNLAT KFKCHDVVID TCRDLKDRQQ LLAYRSKVDK GSAEEEKIDA ILSSSQIRWK N
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B. May play a role in vesicular trafficking during spermatogenesis. May be involved in direct or indirect transcriptional regulation of E-cadherin.
  • 基因功能参考文献：
    1. VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function PMID: 29409756
  • 亚细胞定位：
    Cytoplasm. Cytoplasmic vesicle. Early endosome. Recycling endosome. Late endosome.
  • 蛋白家族：
    SPE39 family
  • 数据库链接：

    KEGG: mmu:104799

    STRING: 10090.ENSMUSP00000072527

    UniGene: Mm.208750