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Recombinant Mouse Retbindin (Rtbdn)

  • 货号:
    CSB-YP020560MO
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 货号:
    CSB-EP020560MO
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 货号:
    CSB-EP020560MO-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 货号:
    CSB-BP020560MO
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 货号:
    CSB-MP020560MO
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Rtbdn
  • Uniprot No.:
  • 别名:
    RtbdnRetbindin
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    Full Length of Mature Protein
  • 表达区域:
    32-247
  • 氨基酸序列
    HPLQTRSWG HPGLAAKVRT GQLQPAGHPQ SSVLPSYPRI QVPGSQTPPV PVPCCTAEID RPESLLESCG APSPECEFFL GQLQGALRDR FHPQLFGARP VQPLCPELCQ IWFTTCQADF ICGPTWLQSS GERGCEPSCR TYGQTFANAT DLCHSVLGHV LRVAAPGSSH CLNVSISSPG ARRRPRAWIS NVVGSGSGSG SGDSPEPMFG FQYVSLP
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Riboflavin-binding protein which might have a role in retinal flavin transport.
  • 基因功能参考文献:
    1. Retbindin ablation causes a retinal phenotype characterized by time- and dose-dependent declines in rod and cone photoreceptor functions as early as 120 days of age. Whereas minor retinal ultrastructural defects were observed at all ages examined, a significant decline occurred in photoreceptor nuclei at 240 days of age ( approximately 36.8% rods and approximately 19.9% cones). PMID: 29079576
    2. Data suggest Retbindin as a possible flavin binding protein in the neural retina. PMID: 26427470
    3. retbindin is an excellent candidate for binding retinal flavins and possibly participating in their transport from the extracellular space to the photoreceptors. PMID: 25542898
  • 亚细胞定位:
    Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Cell membrane; Peripheral membrane protein.
  • 蛋白家族:
    Folate receptor family
  • 组织特异性:
    Expressed in the peripheral retina where it localizes to the inter-photoreceptor matrix (at protein level). May be produced by rod photoreceptors (at protein level).
  • 数据库链接:

    KEGG: mmu:234542

    UniGene: Mm.461701