Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse Prostate stem cell antigen (Psca)

Recombinant Mouse Prostate stem cell antigen (Psca)

In Stock
  • 货号：
    CSB-YP018840MO
  • 规格：
    ￥1836
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 别名：
    Psca; Prostate stem cell antigen
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    Yeast
  • 分子量：
    10.4kDa
  • 表达区域：
    21-95aa
  • 氨基酸序列
    LQCYSCTAQMNNRDCLNVQNCSLDQHSCFTSRIRAIGLVTVISKGCSSQCEDDSENYYLGKKNITCCYSDLCNVN
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

问答及客户评论

■ 常见问题解答
Q:

Would you be able to confirm whether or not CSB-YP018840MO - Mouse PSCA Recombinant (His) Protein is supplied as a monomer or a dimer?

A:
Very nice to receive your inquiry. CSB-YP018840MO Recombinant Mouse Prostate stem cell antigen(Psca)
(If the order quantity is smaller than 0.1mg, then the lead time will be 5-7 working days. If the order quantity is larger than 0.1mg. )
We haven't tested whether this protein is a monomer or a dimer. Primarily, judged by SDS-PAGE, it is a monomer.
However, we need to combine with non-denatured gel to determine whether it is a monomer or a dimer.
If you need, we could arrange for non-denatured gel testing. This service is free of charge and it will take 2-3 working days to get the result.

靶点详情

  • 功能：
    May be involved in the regulation of cell proliferation.; May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.
  • 基因功能参考文献：
    1. Increase in prostate stem cell antigen expression in prostatic hyperplasia induced by testosterone and 17beta-estradiol in C57BL mice PMID: 26815912
    2. This transgenic system helps define the range of cellular changes associated with altered expression of PSCA, shows that transcriptional control is a major component regulating PSCA levels. PMID: 11752398
    3. Sca-1-enriched prostate-regenerating cells possess multiple stem/progenitor cell properties PMID: 15860580
    4. PSCA may play a role in limiting prostate tumor progression in certain contexts, and deletion of PSCA may promote tumor migration and metastasis. PMID: 18044730
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 组织特异性：
    Predominantly expressed in prostate. Also found in spleen, liver, lung, prostate, kidney and testis. Expressed in brain cortex; expression is increased in transgenic mouse model of Alzheimer disease (at protein level).
  • 数据库链接：

    KEGG: mmu:72373

    STRING: 10090.ENSMUSP00000023265

    UniGene: Mm.46395