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Recombinant Mouse Prolargin (Prelp)

  • 货号:
    CSB-YP884937MO
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 货号:
    CSB-EP884937MO
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 货号:
    CSB-EP884937MO-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 货号:
    CSB-BP884937MO
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 货号:
    CSB-MP884937MO
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Prelp
  • Uniprot No.:
  • 别名:
    Prelp; Prolargin; Proline-arginine-rich end leucine-rich repeat protein
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    Full Length of Mature Protein
  • 表达区域:
    22-378
  • 氨基酸序列
    QPTRPKPGI RRKPKPRPTP RFPQAPEPAE PTDLPPPLPP GPPSVFPDCP RECYCPPDFP SALYCDSRNL RRVPVIPPRI HYLYLQNNFI TELPLESFQN ATGLRWVNLD NNRIRKVDQR VLGKLPSLAF LYMEKNQLEE VPSALPRNLE QLRLSQNLIS RIPPGVFSKL ENLLLLDLQH NRLSDGVFKA DTFQGLKNLM QLNLAHNILR KMPPKVPQAI HQLYLDSNKI ETIPNGYFKD FPNLAFIRMN YNKLSDRGLP KNSFNISNLL VLHLSHNKIS NVPAISNKLE HLYLNNNSIE KINGTQICPN NLVAFHDFSS DLENVPHLRY LRLDGNFLKP PIPLDLMMCF RLLQSVVI
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    May anchor basement membranes to the underlying connective tissue.
  • 基因功能参考文献:
    1. Therefore, this study established a new role of PRELP in modulating beta-catenin/connexin43 pathway and osteoblast differentiation. PMID: 26809092
    2. when delivered via an AAV vector to the retina of mice, PRELP inhibited laser-induced choroidal neovascularization by 60%. PRELP reduced deposition of membrane attack complex in vivo by 25.5%. PMID: 24670995
    3. PRELP has a role in skeletal remodeling. PMID: 19951916
    4. expressed in cartilage throughout both fetal development and post-natal life PMID: 11731272
  • 亚细胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily
  • 组织特异性:
    Expressed in cartilage throughout both fetal development and postnatal life. It is also expressed in the developing embryo prior to skeletogenesis. In adult, highest expression in lung, lower levels in cardiac and skeletal muscle.
  • 数据库链接:

    KEGG: mmu:116847

    STRING: 10090.ENSMUSP00000048803

    UniGene: Mm.214514