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  4. Recombinant Mouse Peptidyl-prolyl cis-trans isomerase FKBP10 (Fkbp10)

Recombinant Mouse Peptidyl-prolyl cis-trans isomerase FKBP10 (Fkbp10)

  • 货号：
    CSB-YP726752MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP726752MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP726752MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP726752MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP726752MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Fkbp10; Fkbp-rs; Fkbp1-rs; Fkbp6; Fkbp65; FkbprpPeptidyl-prolyl cis-trans isomerase FKBP10; PPIase FKBP10; EC 5.2.1.8; 65 kDa FK506-binding protein; 65 kDa FKBP; FKBP-65; FK506-binding protein 10; FKBP-10; Immunophilin FKBP65; Rotamase
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    34-581
  • 氨基酸序列
    SPAGAPL EDVVIERYHI PRACPREVQM GDFVRYHYNG TFEDGKKFDS SYDRSTLVAI VVGVGRLITG MDRGLMGMCV NERRRLIVPP HLGYGSIGVA GLIPPDATLY FDVVLLDVWN KADTVQSTIL LRPPYCPRMV QNSDFVRYHY NGTLLDGTAF DNSYSRGGTY DTYIGSGWLI KGMDQGLLGM CPGEKRKIII PPFLAYGEKG YGTVIPPQAS LVFYVLLLDV HNPKDTVQLE TLELPQGCVR RAVAGDFMRY HYNGSLMDGT LFDSSYSRNH TYNTYVGQGY IIPGMDQGLQ GACIGERRRI TVPPHLAYGE NGTGDKIPGS AVLIFDVHVI DFHNPSDPVE IKTLSRPPEN CNETSKIGDF IRYHYNCSLL DGTRLFSSHD YEAPQEITLG ANKVIEGLDR GLQGMCVGER RQLIVPPHLA HGENGARGVP GSAVLLFEVE LVSREDGLPT GYLFVWYQDP STSLFEDMDL NKDGEVPPEE FSSFIKAQVN EGKGRLMPGQ DPDKTISDMF QNQDRNQDGK ITAEELKLKS DEDQERVHEE L
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    PPIases accelerate the folding of proteins during protein synthesis.
  • 基因功能参考文献：
    1. FKBP65 regulates LH2-mediated collagen cross-linking. PMID: 28378777
    2. the altered collagen crosslinking through Fkbp10 ablation in osteoblasts primarily leads to a qualitative defect in the skeleton. PMID: 28206698
    3. FKBP10 plays a crucial role in hypertrophic scar formation and maybe a therapeutic target for hypertrophic scars. PMID: 28774593
    4. Data suggest a requirement for FKBP65 function during embryonic connective tissue development in mice; its expression is restricted postnatally in bone, ligaments and tendons. PMID: 24777781
    5. FKBP65 may act as an elastin chaperone in vivo by controlling both the coacervation and the maturation stages of its selfassembly into fibrils. PMID: 21102654

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  • 亚细胞定位：
    Endoplasmic reticulum lumen.
  • 组织特异性：
    Expressed in aorta, brain, kidney, and lung.
  • 数据库链接：

    KEGG: mmu:14230

    STRING: 10090.ENSMUSP00000001595

    UniGene: Mm.3894