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  4. Recombinant Mouse PHD finger protein 19 (Phf19)

Recombinant Mouse PHD finger protein 19 (Phf19)

  • 货号：
    CSB-YP017907MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP017907MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP017907MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP017907MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP017907MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Phf19
  • Uniprot No.：
  • 别名：
    Phf19; Pcl3; PHD finger protein 19; Polycomb-like protein 3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-578
  • 氨基酸序列
    METQALEPGT LEAFGATSPN KGGLSKTKKN FKDLMSKVTE GQFVLCRWTD GLYYLGKIKR VSSPKQSCLV TFEDNSKYWV LWKDIQHAGV PGEEPKCDVC MGKTSGPMNE ILICGKCGLG YHQQCHIPIA VDANWPLLTH WFCRRCIFAL AVRKGGALKK GAIAKTLQAV KMVLSYQPEE LDWDSPHRTN QQQCYCYCGG PGEWYLRMLQ CYRCRQWFHE ACTQCLSEPM VFGDRFYLFF CSVCNQGPEY IERLPLRWVD IVHLALYNLG VQSKKRYFDF EEILAFVNHH WELLQLGKLT STPMTERGPH LLNALNSYKS RFLCGKEIKK KKCIFRLRIR VPPAPPGKLL PDRALMPSDK GTSELLRKKG KSKPGLLPQE PQQQKRRVYR RKRSKFLLED AIPSSDFTSA WSTDHHLASI FDFTLDEIQS LKSGSSGQTF FSDVDSTDAA STSGSASTSL SYDSRWTVGS RKRKLTAKVH RPLRAKQRAA ELEGRCASDS NAEGAVGPEQ PDEGIDSHTL ESISGDDSSL SHLKSSITNY FGAAGRLACG EKYRVLARRV TPEGKVQYLL EWEGTTPY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds histone H3 dimethylated at 'Lys-36' (H3K36me2).
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Polycomblike family
  • 数据库链接：

    KEGG: mmu:74016

    STRING: 10090.ENSMUSP00000028232

    UniGene: Mm.65691