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  4. Recombinant Mouse Oligodendrocyte-myelin glycoprotein (Omg)

Recombinant Mouse Oligodendrocyte-myelin glycoprotein (Omg)

  • 货号：
    CSB-YP737233MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP737233MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP737233MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP737233MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP737233MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Omg; OmgpOligodendrocyte-myelin glycoprotein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    25-417
  • 氨基酸序列
    ICPLQC TCTERHRHVD CSGRNLTTLP PGLQENIIHL NLSYNHFTDL HNQLTPYTNL RTLDISNNRL ESLPAQLPRS LWNMSAANNN IKLLDKSDTA YQWNLKYLDV SKNMLEKVVL IKNTLRSLEV LNLSSNKLWT VPTNMPSKLH IVDLSNNSLT QILPGTLINL TNLTHLYLHN NKFTFIPEQS FDQLLQLQEI TLHNNRWSCD HKQNITYLLK WVMETKAHVI GTPCSKQVSS LKEQSMYPTP PGFTSSLFTM SEMQTVDTIN SLSMVTQPKV TKTPKQYRGK ETTFGVTLSK DTTFSSTDRA VVAYPEDTPT EMTNSHEAAA ATLTIHLQDG MSSNASLTSA TKSPPSPVTL SIARGMPNNF SEMPRQSTTL NLRREETTAN GNTRPPS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
  • 基因功能参考文献：
    1. study provided in vitro and in vivo evidence that endogenous OMgp plays an important role in oligodendrocyte differentiation and myelination PMID: 21352918
    2. While myelin-derived axon growth inhibitor OMG may modulate axon sprouting, it does not play a major role in central nervous system axon regeneration failure. PMID: 20547125
    3. This allelic series will aid in the study of OMgp in adult CNS axon regeneration using mouse models of spinal cord injury. PMID: 19672953
    4. Expression of Omg protein in the embryonic mouse telencephalon indicates Omg has a role in axonal target specification and synaptic plasticity. PMID: 19892785
    5. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. PMID: 12068310

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 组织特异性：
    Oligodendrocytes and myelin of the central nervous system.
  • 数据库链接：

    KEGG: mmu:18377

    STRING: 10090.ENSMUSP00000132918

    UniGene: Mm.93335