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  4. Recombinant Mouse Nucleoplasmin-2 (Npm2)

Recombinant Mouse Nucleoplasmin-2 (Npm2)

  • 货号：
    CSB-YP768893MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP768893MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP768893MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP768893MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP768893MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Npm2
  • Uniprot No.：
  • 别名：
    Npm2; Nucleoplasmin-2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-207
  • 氨基酸序列
    MSRHSTSSVT ETTAKNMLWG SELNQEKQTC TFRGQGEKKD SCKLLLSTIC LGEKAKEEVN RVEVLSQEGR KPPITIATLK ASVLPMVTVS GIELSPPVTF RLRTGSGPVF LSGLECYETS DLTWEDDEEE EEEEEEEDED EDADISLEEI PVKQVKRVAP QKQMSIAKKK KVEKEEDETV VRPSPQDKSP WKKEKSTPRA KKPVTKK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.
  • 基因功能参考文献：
    1. Findings demonstrate that the NPM2-based oocyte nucleolus is an essential platform for parental chromatin organization in early embryonic development. PMID: 28600324
    2. involved in sperm chromatin remodeling PMID: 21415138
    3. NPM2 targeting of nucleolus-like bodies (NLBs) is regulated by the K-rich motif and is essential for the formation of NLBs. PMID: 19805576
    4. Npm2 is a maternal effect gene critical for nuclear and nucleolar organization and embryonic development PMID: 12714744
    5. The highest Npm2 mRNA levels were detected in oocytes in the pre-antral follicle stage. PMID: 19553355

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  • 亚细胞定位：
    Nucleus. Note=Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.
  • 蛋白家族：
    Nucleoplasmin family
  • 组织特异性：
    Ovary specific.
  • 数据库链接：

    KEGG: mmu:328440

    STRING: 10090.ENSMUSP00000057365

    UniGene: Mm.347749