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  4. Recombinant Mouse NADPH oxidase activator 1 (Noxa1)

Recombinant Mouse NADPH oxidase activator 1 (Noxa1)

  • 货号：
    CSB-YP015963MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP015963MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP015963MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP015963MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP015963MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Noxa1
  • Uniprot No.：
  • 别名：
    Noxa1NADPH oxidase activator 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-444
  • 氨基酸序列
    MSSLGDQIRD WHRGVLAVAR EDWDSALCFF SDVREPLARM YFNRGCVHLM AGDPEAALRA FDQAVTKDTC MAVGFLQRGV ANFQLQRFQE AVSDFQLALA QLRDNAVIDY TQLGLNFKLQ AWEVLYNMAS AQCQAGLWTK AANTLVEAIS KWPEGAQDIL DIAMDKVQKQ VPLQLQQVPK GEVFQPPRRY LKHLEPMDFL GKAKVVASVI PDDHNAQPQQ RSQAEHAGHQ PSSSMCKRVL STTGGHTSPG LYDSLLASRR PGPGPSEVSS GSEGAATKDP ESLVTVTVQC HFTVPLKVPR GTGLSSFQTL LAQALLHQTQ TGQLSYKAPG EERSWIPIST EESLQSIWRN VPVGPGGLQL QCQGVWGRPV LYQVVAQYNY RAQRPEDLDF HQGDTVDVLC EVDEAWLEGH RDGCVGIFPK CFVVPAGAYV EAMLVLGPQP GDQN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.
  • 基因功能参考文献：
    1. NoxA1 is the functional homolog of p67phox in vascular smooth muscle cells (VSMC) that regulates redox signaling and VSMC phenotype. PMID: 20083677
  • 亚细胞定位：
    Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1.
  • 蛋白家族：
    NCF2/NOXA1 family
  • 组织特异性：
    Widely expressed with a tissue distribution similar to the one of NOX1. Detected in colon, uterus, prostate, small intestine, stomach, lung, thyroid, aorta, inner ear and salivary glands. Expressed in colon, small intestine and aortic smooth muscle cells
  • 数据库链接：

    KEGG: mmu:241275

    STRING: 10090.ENSMUSP00000037423

    UniGene: Mm.218774