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  4. Recombinant Mouse Kinesin-like protein KIF22 (Kif22)

Recombinant Mouse Kinesin-like protein KIF22 (Kif22)

  • 货号：
    CSB-YP659768MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP659768MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP659768MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP659768MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP659768MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Kif22
  • Uniprot No.：
  • 别名：
    Kif22Kinesin-like protein KIF22
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-660
  • 氨基酸序列
    MSLRAKTCPQ RREMASATSG PGRCVSKGGL GRRPPLARVR VAVRLRPFMD GETEAKELPC VRAIDSCSLE VANWKKYQET LKYQFDAFYG EKSTQQEVYV GSVQPILRHL LEGQNASVLA YGPTGAGKTH TMLGSPEQPG VIPRALMDLL QLAREESAEG RPWDVSVAMS YLEIYQEKVL DLLDPASGDL VIREDCRGNI LIPGLTQKPI TSFSDFEQHF LPASRNRAVG ATRLNQRSSR SHAVLLVKVD QRERLTPFRQ REGKLYLIDL AGSEDNRRTG NQGIRLKESG AINTSLFVLG KVVDALNQGL PRIPYRDSKL TRLLQDSLGG SAHSILIANI APERRFYQDT ISALNFTARS KEVINRPFTN ESLQPHALAP VKLSQKELLG PSEAKKAKGP EEESTGSPES TAAPASASQK LSLLQKLSNM DPAMLENLLS MERLLGSQGS QGTPLLNTPK RERMVLMKTV EEKNLEIERL KMKQKELEAK VLAQEAPDPR EKENTPTILQ PPASYSGTVA KPLKKAVVMP LQRIQKQRES SNQIQLLKKG PKRKLEPSPE SEAVEKDEDY WEVQISPELL AHGRKKLLDL LNEGSARELR SLQRIGQKKA QLIVGWRELH GPFSEVEDLE QVEGISGKQV ESFLKANLLS LAASQHSGPS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells.
  • 基因功能参考文献：
    1. phosphorylation of Thr463 switches the mitotic chromosome movement from an anti-poleward direction to a poleward direction by converting the Kid functional mode from polar-ejection-force-ON to -OFF during the metaphase-anaphase transition. PMID: 27550518
    2. These data suggest that Kid-mediated anaphase/telophase chromosome compaction prevents formation of multinucleated cells. PMID: 18329364
  • 亚细胞定位：
    Nucleus. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 数据库链接：

    KEGG: mmu:110033

    STRING: 10090.ENSMUSP00000032915

    UniGene: Mm.286488