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  4. Recombinant Mouse HMG box-containing protein 1 (Hbp1)

Recombinant Mouse HMG box-containing protein 1 (Hbp1)

  • 中文名称：
    小鼠Hbp1重组蛋白
  • 货号：
    CSB-YP851261MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Hbp1重组蛋白
  • 货号：
    CSB-EP851261MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Hbp1重组蛋白
  • 货号：
    CSB-EP851261MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Hbp1重组蛋白
  • 货号：
    CSB-BP851261MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Hbp1重组蛋白
  • 货号：
    CSB-MP851261MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Hbp1
  • Uniprot No.：
  • 别名：
    Hbp1HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-516
  • 氨基酸序列
    MVWEVKTNQM PNAVQKLLLV MDKRAPGMSD SLELLQCNEN LPSSPGYNSC DEHMELDDLP ELQAVQSDPT QSAIYQLSSD VSHQEYPRSS WSQNTSDIPE NTHREDEVDW LTELANIATS PQSPLMQCSF YNRSSPVHII ATSKSLHSYA RPPPVSSSSK SGPAFPHDHW KEETPVRHER ANSESESGIF CMSSLSDDDD LGWCNSWPST IWHCFLKGTR LCFHKESNKE WQDVEDFARA ASCDNEEEIQ MGTHKGYGSD GLKLLSHEES VSFGESVLKL TFDPGTVEDG LLTVECKLDH PFYVKNKGWS SFYPSLTVVQ HGIPCCEIHI GDVCLPPGHP DAINFDDSGV FDTFKSYDFT PMDSSAVYVL SSMARQRRAS LSCGGGPGTG QEFSGSEFSK SCGSPGSSQL SSSSLYAKAV KSHSSGTVSA TSPNKCKRPM NAFMLFAKKY RVEYTQMYPG KDNRAISVIL GDRWKKMKNE ERRMYTLEAK ALAEEQKRLN PDCWKRKRTN SGSQQH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
  • 基因功能参考文献：
    1. the regulation of Hbp1 conferred substantial protection of ovarian reserve. PMID: 27206316
    2. new regulatory pathway of YY1/HDACs/miR-155/HBP1 in macrophage-derived foam cell formation during early atherogenesis PMID: 24675724
    3. identify the high-mobility group box protein HBP1 transcriptional repressor as a new substrate for p38 MAP kinase PMID: 14612426
    4. Hbp1 is up-regulated specifically in germ cells of the developing XY gonad PMID: 15162515
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: mmu:73389

    STRING: 10090.ENSMUSP00000131158

    UniGene: Mm.390461