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  4. Recombinant Mouse Guanine nucleotide-binding protein G (I)/G (S)/G (O) subunit gamma-13 (Gng13)

Recombinant Mouse Guanine nucleotide-binding protein G (I)/G (S)/G (O) subunit gamma-13 (Gng13)

  • 中文名称：
    小鼠Gng13重组蛋白
  • 货号：
    CSB-YP888363MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Gng13重组蛋白
  • 货号：
    CSB-EP888363MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Gng13重组蛋白
  • 货号：
    CSB-EP888363MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Gng13重组蛋白
  • 货号：
    CSB-BP888363MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Gng13重组蛋白
  • 货号：
    CSB-MP888363MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Gng13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-64
  • 氨基酸序列
    MEEWDVPQMK KEVESLKYQL AFKREMSSKT IPELLKWIED GIPKDPFLNP DLMKNNPWVE KAKC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
  • 基因功能参考文献：
    1. Differential function of Ggamma13 in rod bipolar and ON cone bipolar cells PMID: 25416620
    2. The results of this study indicated that Galphaolf exclusively forms a functional heterotrimeric G-protein with Gbeta1 and Ggamma13 in OSNs, mediating olfactory signal transduction PMID: 23637188
    3. Data suggest that proteins of the taste transduction cascade (alpha-gustducin, G-protein gamma13, and phospholipase Cbeta2) are expressed in testis and are involved in spermatogenesis. PMID: 22266327
    4. Ggamma13 subunit is coexpressed in physiologically ON-type cone bipolar cells with Gbeta3 and Gbeta4 but is not present in OFF-type bipolar cells. PMID: 12454992
    5. Ggamma13 interacts with PDZ domain-containing proteins PMID: 16473877
    6. Gng13 mRNA is highly restricted to the cortex of the XX gonad during sexual differentiation, suggesting a role for this gene during ovarian development. PMID: 17497668
    7. Ggamma13, a divergent member of the Ggamma subunit family, is abundantly expressed in the cilia of olfactory sensory neurons and and interacts with Ric-8B. PMID: 18462949

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    G protein gamma family
  • 数据库链接：

    KEGG: mmu:64337

    STRING: 10090.ENSMUSP00000110760

    UniGene: Mm.171123