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  4. Recombinant Mouse F-box only protein 33 (Fbxo33)

Recombinant Mouse F-box only protein 33 (Fbxo33)

  • 中文名称：
    小鼠Fbxo33重组蛋白
  • 货号：
    CSB-YP855339MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Fbxo33重组蛋白
  • 货号：
    CSB-EP855339MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Fbxo33重组蛋白
  • 货号：
    CSB-EP855339MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Fbxo33重组蛋白
  • 货号：
    CSB-BP855339MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Fbxo33重组蛋白
  • 货号：
    CSB-MP855339MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Fbxo33
  • Uniprot No.：
  • 别名：
    Fbxo33F-box only protein 33; AIG30-12-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-562
  • 氨基酸序列
    MLLFLSVPQP RPPGARTRAG AARLVRWRRR QRLRLLQLRR LRGLLRGLRR RPGTGGRRPS RMALCGQAAG AASLPSELIV HIFSFLPAPD RLRASASCSH WRECLFYPAL WPQLRICLRV SPAEQPRLEF LMRKCGWFVR ELRVEFAAEN YLSGGGGPGD GGSGGGTDTG TGGEDGEALQ LSSRWLEVLR IYLELVLCVL LSIRNNRNLQ KFSLFGDISV VHQQGSLSST YLSRVDPDGK KIKQIQQLFE EILSNSRQLK WLSCGFMLEI VTPTSLSSLS NPIANTMEHL SLLDNNIPGN STLITAVELE RFVNLRSLAL DFCDFTAEMA RVLTDSNHVP LQRLSLLVHN ASVMLKSLDN MPNDEHWKAL SRKSSSLRVY LMVFDIKSED MLKILKPSIP LERVHFDSYV TCVSGAIVDL ISRQYDKFLT HFILMNDMID TSGFPDLSDN RNEDPLVLLA WRCTKLTLLA IHGYTVWAHN LIAIARLRGS DLKVLQVTEE SIDFDQGELA DQDVDPVQNL IEQVSLGLGQ SWHAVLDIES LSVFTEPNRH FYREMQSFSE DI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.
  • 基因功能参考文献：
    1. mRNA expression in the hippocampus 1 h following generalized convulsive seizure, in a pattern which is typical for other activity-dependant genes expressed in this structure. PMID: 15380003
    2. FBX33 as a component of an SCF E3-ubiquitin ligase that targets the multifunctional regulator Y-box binding protein 1 (YB-1)/dbpB/p50 for polyubiquitination and destruction by the proteasome. PMID: 16797541
  • 数据库链接：

    KEGG: mmu:70611

    STRING: 10090.ENSMUSP00000035948

    UniGene: Mm.311026