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  4. Recombinant Mouse Cyclin-G2 (Ccng2)

Recombinant Mouse Cyclin-G2 (Ccng2)

  • 货号：
    CSB-YP004821MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP004821MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP004821MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP004821MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP004821MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Ccng2; Cyclin-G2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-344
  • 氨基酸序列
    MKDLGAKHLA GGEGVQLFGL LNFYLEQEQR YQPREKGLIL MEATPENDNT LCSRLRNAKV EDLRSLTNFF GSGTETFVLA VNILDRFLAL MKVKPKHLSC IGVCCFLLAA RLAEEEGDVP PTHDVIRISQ CKCTASDIKR MEKIISEKLH YELEATTALN FLHLYHAIVF CHTSERKEIL SLDKLEAQLK ACNCRVVFSK ARPSVLALCL LNLEIETIKS VELLEILLLV KKHLKLSDTE FFYWRELVSK CLAEYSSPRC CKPDLKKLVW IVSRRTAQNL HSSYYSVPEL PTIPEGGCFD GSESEDSGED MSCGEESLSS SPPSDQECTF FFDFQVAQTL CFPP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in growth regulation and in negative regulation of cell cycle progression.
  • 基因功能参考文献：
    1. Single or double knockout mice deficient in CycG1 or CycG2, or both showed that all developed normally and were fertile. Generation of mouse embryonic fibroblasts (MEFs) from these mice revealed that G2KO MEFs were resistant to DNA damage insults caused by camptothecin and ionizing radiation and underwent cell cycle arrest. PMID: 27982046
    2. CycG2 controls the dephosphorylation of the DNA repair-related factors gammaH2AX and CHK2-pT68 at DNA repair foci. PMID: 23656780
    3. our results demonstrate a novel role for cyclin G2 in the regulation of adipogenesis. PMID: 20844002
    4. These results show that FoxO genes regulate cyclin G2 expression, illustrating a new role for phosphoinositide 3-kinase and FoxO transcription factors in the control of cell cycle entry. PMID: 14966295
  • 亚细胞定位：
    Cytoplasm. Nucleus. Note=Primarily found in the cytoplasm. A minor portion can be detected in some cells in the nucleus.
  • 蛋白家族：
    Cyclin family, Cyclin G subfamily
  • 组织特异性：
    Highest levels in intestine. Intermediate levels in spleen, brain and kidney. Low levels in testis, stomach, pancreas, liver, salivary gland and muscle. According to PubMed:9139721 also abundant in thymus.
  • 数据库链接：

    KEGG: mmu:12452

    STRING: 10090.ENSMUSP00000031331

    UniGene: Mm.3527