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  4. Recombinant Mouse Cell death activator CIDE-B (Cideb)

Recombinant Mouse Cell death activator CIDE-B (Cideb)

  • 货号：
    CSB-YP005432MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP005432MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP005432MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP005432MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP005432MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cideb
  • Uniprot No.：
  • 别名：
    CidebCell death activator CIDE-B; Cell death-inducing DFFA-like effector B
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-219
  • 氨基酸序列
    MEYLSAFNPN GLLRSVSTVS SELSRRVWNS APPPQRPFRV CDHKRTVRKG LTAASLQELL DKVLETLLLR GVLTLVLEED GTAVDSEDFF QLLEDDTCLM VLEQGQSWSP KSGMLSYGLG REKPKHSKDI ARITFDVYKQ NPRDLFGSLN VKATFYGLYS MSCDFQGVGP KRVLRELLRW TSSLLQGLGH MLLGISSTLR HVVEGADRWQ WHGQRHLHS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Activates apoptosis.
  • 基因功能参考文献：
    1. High Cideb expression is associated with Ulcerative Colitis. PMID: 28719542
    2. these data revealed that Cideb plays an important role in controlling intestinal chylomicron lipidation. PMID: 24831470
    3. Cideb and perilipin 2 play opposing roles in controlling VLDL lipidation and hepatic lipid homeostasis PMID: 22661308
    4. SREBP-1c mediates the effect of insulin on the expression of Cidea in mouse hepatocytes. PMID: 20575761
    5. Data suggest that Cideb is a novel regulator in controlling cholesterol homeostasis in the liver. PMID: 20123130
    6. Cideb is a novel important regulator in lipid metabolism in the liver and may thus represent a new therapeutic target for the treatment of obesity, diabetes, and liver steatosis PMID: 17646209
    7. Cideb protein promotes the formation of triacylglycerol-enriched VLDL particles and provides a molecular insight into VLDL lipidation and maturation in hepatocytes. PMID: 19187774

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  • 数据库链接：

    KEGG: mmu:12684

    STRING: 10090.ENSMUSP00000001497

    UniGene: Mm.466766