Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse Cation channel sperm-associated protein 3 (Catsper3), partial

Recombinant Mouse Cation channel sperm-associated protein 3 (Catsper3), partial

  • 中文名称：
    Recombinant Mouse Cation channel sperm-associated protein 3(Catsper3),partial,Yeast
  • 货号：
    CSB-YP802240MO1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Cation channel sperm-associated protein 3(Catsper3),partial,Yeast
  • 货号：
    CSB-EP802240MO1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Cation channel sperm-associated protein 3(Catsper3),partial,Yeast
  • 货号：
    CSB-EP802240MO1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Cation channel sperm-associated protein 3(Catsper3),partial,Yeast
  • 货号：
    CSB-BP802240MO1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Cation channel sperm-associated protein 3(Catsper3),partial,Yeast
  • 货号：
    CSB-MP802240MO1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Catsper3
  • Uniprot No.：
  • 别名：
    Catsper3; Cation channel sperm-associated protein 3; CatSper3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization.
  • 基因功能参考文献：
    1. Data suggest that Catsper1, Catsper2, Catsper3, and Catsper4 form protein multimer with hypothetical activities of flippase and disulfide isomerase. PMID: 29371110
    2. Hydrogen peroxide induced upregulation of catsper3 in brain. PMID: 20586097
    3. Catsper3 has a single channel-forming domain, a pore-loop with the consensus sequence TxDxW, & a coiled-coil protein-protein interaction domain in the C-terminal tail. CatSpers 1,2,3 & 4 may interact directly or indirectly to form a functional tetramer. PMID: 12932298
    4. CATSPER3 is a cation-channel protein and has role in acrosome reaction and male fertility PMID: 16107607
    5. Catsper3 and Catsper4 knockout male mice are completely infertile due to a quick loss of motility and a lack of hyperactivated motility under capacitating conditions. PMID: 17344468
    6. Data show that spinal cord injury doesn't significantly change the expression of CatSpers 3. PMID: 18607386

    显示更多

    收起更多

  • 亚细胞定位：
    Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail.
  • 蛋白家族：
    Cation channel sperm-associated (TC 1.A.1.19) family
  • 组织特异性：
    Testis-specific.
  • 数据库链接：

    KEGG: mmu:76856

    STRING: 10090.ENSMUSP00000021961

    UniGene: Mm.159795