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  4. Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1)

Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1 (Camk2n1)

  • 中文名称：
    Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1(Camk2n1),Yeast
  • 货号：
    CSB-YP004469MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1(Camk2n1),Yeast
  • 货号：
    CSB-EP004469MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1(Camk2n1),Yeast
  • 货号：
    CSB-BP004469MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Calcium/calmodulin-dependent protein kinase II inhibitor 1(Camk2n1),Yeast
  • 货号：
    CSB-MP004469MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Camk2n1
  • Uniprot No.：
  • 别名：
    Camk2n1Calcium/calmodulin-dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor alpha; mCaMKIINalpha
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-78
  • 氨基酸序列
    MSEVLPYGDE KLSPYGDGGD VGQIFSCRLQ DTNNFFGAGQ SKRPPKLGQI GRSKRVVIED DRIDDVLKTM TDKAPPGV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potent and specific inhibitor of CaM-kinase II (CAMK2).
  • 基因功能参考文献：
    1. Camk2n1 down-regulation caused dorsal striatum-related cognitive disorders by inhibiting synaptic plasticity. PMID: 28890075
    2. The mouse Ca2+/calmodulin kinase II inhibitor alpha (CaMKIINalpha) gene encodes a 2.9kb brain-specific transcript whose expression is downregulated in mouse brain during Japanese encephalitis virus and rabies virus infection. PMID: 17010311
    3. hCaMKIINbeta may play an important role in the regulation of tumor cell growth PMID: 19586909
    4. Camk2n1 mRNA expression is down regulated in mouse brain during virus infection PMID: 17010311
    5. Camk2n1 was shown to be a 37 kDa protein localized in the post synaptic density (PSD) of mouse brain PMID: 17350603

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  • 亚细胞定位：
    Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density.
  • 蛋白家族：
    CAMK2N family
  • 组织特异性：
    Brain specific (at protein level).
  • 数据库链接：

    KEGG: mmu:66259

    STRING: 10090.ENSMUSP00000060349

    UniGene: Mm.41603