Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse CREB/ATF bZIP transcription factor (Crebzf)

Recombinant Mouse CREB/ATF bZIP transcription factor (Crebzf)

  • 货号：
    CSB-YP005956MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP005956MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP005956MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-MP005956MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Crebzf
  • Uniprot No.：
  • 别名：
    Crebzf; ZfCREB/ATF bZIP transcription factor; Host cell factor-binding transcription factor Zhangfei; HCF-binding transcription factor Zhangfei; Tyrosine kinase-associated leucine zipper protein LAZip
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-358
  • 氨基酸序列
    MRHSLTKLLA ASGRDFPSRR DSREPPATRA PPREPSGAAA GAETPRPGSP DREQPHGDGD GGEPEARSGS RGSVAVRAPA PSPLKMEEEE EDAIAMVPKE EPEDMDFLSG LELADLLDPR QPDWHLEPGL SSPGPLSSSG GGSESGGLLR GDDDDDTAAA EMQRFSDLLQ RLLNGIGGCS SGGDRGGGEK RRRKSPGAGG GGANDGNQAA TKSPRKAAAA AARLNRLKKK EYVMGLESRV RGLAAENQEL RAENRELGKR VQALQEESRY LRAVLANETG LARLLSRLSG VGLRLTTSLF RDSPAGDHDY ALPVGKQPPE PREEDDAAGG VCLHVDKDKV SVEFCSACAR KASSSLKM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
  • 基因功能参考文献：
    1. SMILE is an insulin-inducible corepressor that suppresses hepatic gluconeogenesis. PMID: 26340929
    2. Small heterodimer partner-interacting leucine zipper protein inhibits adipogenesis by regulating peroxisome proliferator-activated receptor gamma activity. PMID: 25896661
    3. Taken together, these findings demonstrate that SMILE negatively regulates osteocalcin via a direct interaction with RUNX2 PMID: 24389415
    4. CREBZF is involved in implantation and is up-regulated by oestrogen. PMID: 24325733
    5. Smile is a novel gene specifying both bronchial smooth muscle and lung alveolar myofibroblast lineages, contributing to our understanding of the biological control of the development of these cells. PMID: 21956870

    显示更多

    收起更多

  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    BZIP family, ATF subfamily
  • 数据库链接：

    KEGG: mmu:233490

    STRING: 10090.ENSMUSP00000102824

    UniGene: Mm.29496