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  4. Recombinant Mouse Ataxin-10 (Atxn10)

Recombinant Mouse Ataxin-10 (Atxn10)

  • 货号：
    CSB-YP002439MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP002439MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP002439MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP002439MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP002439MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Atxn10
  • Uniprot No.：
  • 别名：
    Atxn10; Sca10Ataxin-10; Brain protein E46; Spinocerebellar ataxia type 10 protein homolog
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-475
  • 氨基酸序列
    MAAPRMPPSR LSGIMVPAPI QDLEALRALT ALFKEQRNRE TAPRTIFQRV LDILKKSTHA VELACRDPSQ VEHLASSLQL ITECFRCLRN ACIECSVNQN SIRNLDTIGV AVDLVLLFRE LRVEQDSLLT AFRCGLQFLG NVASRNEESQ SIVWVHAFPE LFMSCLNHPD KKIVAYCSMI LFTSLNAERM KDLEENLNIA INVIEAHQKH PASEWPFLII SDHFLKSPEL VEAMYGKLSN QERITLLDIV IAKLVGEEQL TKDDISIFVR HAELIANSFM DQCRNVLKLT SEPHTEDKEA LVTIRLLDVL CEMTSNTELL GYLQVFPGLM ERVIDVLRVI HEVGKESTNI FSPSDSLKAE GDIEHMTEGF KSHLIRLIGN LCYKNKENQD KVNELDGIPL ILDSSNIDDN NPFMMQWVVY AVRNLTEDNS QNQDVIAKME EQGLADASLL KKMGFEIEKS GDKLILKSNN DIPPP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
  • 基因功能参考文献：
    1. Ataxin-10, encoded by the SCA10 gene, interacts with O-linked N-acetylglucosamine in vivo and is modified by O-linked glycosylation in the insulinoma MIN6 cell line. PMID: 16182253
  • 亚细胞定位：
    Cytoplasm, perinuclear region.
  • 蛋白家族：
    Ataxin-10 family
  • 组织特异性：
    In high cell density areas; cerebellar cortex, dentate gyrus, hippocampus, anterior olfactory nucleus, primary olfactory cortex.
  • 数据库链接：

    KEGG: mmu:54138

    STRING: 10090.ENSMUSP00000132450

    UniGene: Mm.248906