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  4. Recombinant Mouse ADP-ribosylation factor-like protein 6 (Arl6)

Recombinant Mouse ADP-ribosylation factor-like protein 6 (Arl6)

  • 中文名称：
    Recombinant Mouse ADP-ribosylation factor-like protein 6(Arl6),Yeast
  • 货号：
    CSB-YP002093MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse ADP-ribosylation factor-like protein 6(Arl6),Yeast
  • 货号：
    CSB-EP002093MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse ADP-ribosylation factor-like protein 6(Arl6),Yeast
  • 货号：
    CSB-EP002093MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse ADP-ribosylation factor-like protein 6(Arl6),Yeast
  • 货号：
    CSB-BP002093MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse ADP-ribosylation factor-like protein 6(Arl6),Yeast
  • 货号：
    CSB-MP002093MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Arl6
  • Uniprot No.：
  • 别名：
    Arl6; Bbs3; ADP-ribosylation factor-like protein 6
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-186
  • 氨基酸序列
    GLLDRLSGL LGLKKKEVHV LCLGLDNSGK TTIINKLKPS NAQSQDIVPT IGFSIEKFKS SSLSFTVFDM SGQGRYRNLW EHYYKDGQAI IFVIDSSDKL RMVVAKEELD TLLNHPDIKH RRIPILFFAN KMDLRDSVTS VKVSQLLCLE SIKDKPWHIC ASDAIKGEGL QEGVDWLQDQ IQAVKT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization.
  • 基因功能参考文献：
    1. IFT27 prevents aggregation of nucleotide-free ARL6 in solution PMID: 25443296
    2. Bbs3 knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes PMID: 22139371
    3. These data demonstrate that the BBS3L transcript is required for proper retinal function and organization. PMID: 20333246
    4. ARL6 was expressed in the neural plate and probably in the somites PMID: 16172987
  • 亚细胞定位：
    Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Small GTPase superfamily, Arf family
  • 组织特异性：
    Most abundant in brain and kidney. Expressed in heart and eye. Isoform 2 is expressed only in the retina.
  • 数据库链接：

    KEGG: mmu:56297

    STRING: 10090.ENSMUSP00000023405

    UniGene: Mm.392505