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  4. Recombinant Mouse 60 kDa SS-A/Ro ribonucleoprotein (Trove2)

Recombinant Mouse 60 kDa SS-A/Ro ribonucleoprotein (Trove2)

  • 货号：
    CSB-YP025071MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP025071MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP025071MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP025071MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Trove2
  • Uniprot No.：
  • 别名：
    RO60; Ssa2; Trove2; 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; Ro60; RoRNP; TROVE domain family member 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-538
  • 氨基酸序列
    MEGSANQLQP LSETQVVNSE GGCVWQVTDM NRLRRFLCFG SEGGTYYIKE QKLGLENAEA LIRLIEDGRG CEVIQEIKSF SQEGRTAKQE PLLFALAVCS QCADINTKQA AFKAVPEVCR IPTHLFTFIQ FKKDLKESMK CGMWGRALRK AVADWYNEKG GMAVALVVTK YKQRNGWSHK DLLRLSHLKP SSEGLAIVTK YITKGWKEVH EEYKEKALSV EAEKLLKYLE AVEKVKRTKD DLEVIHLIEE HQLVREHLLT NHLKSKEVWK ALLQEMPLTA LLRNLGKMTA NSVLEPGNSE VSLICEKLSN EKLLKKARIH PFHVLIALET YRAGHGLRGK LKWIPDKDIL QALDAAFYTT FKTVEPTGKR FLLAVDVSAS MNQRALGSVL NASTVAAAMC MVVTRTEKES SVVAFACDMV PFPVTTDMTL QQVLTAMNKV PAGNTDCSLP MIWAQKTDTA ADVFVVFTDN ETFAGQVHPA VALREYRKKM DIPAKLIVCG MTSNGFTIAD PDDRGMLDMC GFDTAALDVI RNFTLDVI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation.; May play roles in cilia formation and/or maintenance.
  • 基因功能参考文献：
    1. These data support the hypothesis that antibodies to Ro274 deposit in salivary glands can enter intact salivary gland cells and are involved in the dysregulation of salivary flow in SS. PMID: 25370295
    2. Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDa Ro (SS-A) in experimental autoimmunity. PMID: 12121436
    3. differences in the epitope spreading after 60 kDa Ro peptide immunization in several strains of mice PMID: 12410797
    4. Ro protein has a role in preventing an autoimmune syndrome characterized by anti-ribosome antibodies, anti-chromatin antibodies, and glomerulonephritis PMID: 12788971
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Ro 60 kDa family
  • 组织特异性：
    Highest in brain, followed by lung, muscle, kidney and heart. Lower levels are found in testis, liver and spleen.
  • 数据库链接：

    KEGG: mmu:20822

    STRING: 10090.ENSMUSP00000125623

    UniGene: Mm.40370