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  4. Recombinant Lassa virus Nucleoprotein (N)

Recombinant Lassa virus Nucleoprotein (N)

In Stock
  • 货号：
    CSB-YP356406LCPe1
  • 规格：
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 别名：
    N; Nucleoprotein; EC 3.1.13.-; Nucleocapsid protein; Protein N
  • 种属：
    Lassa virus (strain GA391) (LASV)
  • 蛋白长度：
    Full Length
  • 来源：
    Yeast
  • 分子量：
    62.9 kDa
  • 表达区域：
    1-570aa
  • 氨基酸序列
    MSASKEVRSCLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKQKRDDGDLKRLRDLNQAVNNLVELKSTQQKSVLRVGTLSSDDLLILAADLEKLKSKVTRTERPLSSGVYMGNLSSQQLDQRRALLNMIGMTGVSGGGKGASNGIVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNSSDLDRLSQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKSLGMFVSDTPGERNPYENILYKICLSGDGWSYIASRTSIVGRAWENTVVDLEQDNKPQKIGNGGSNKSLQSAGFAAGLIYSQLMTLKDFKCFNLIPNAKTWMDIEGRPEDPVEIALYQPSSGCYVHFFREPTDLKQFKQDAKYSHGRDVTDLFAAQPGLTSAVIEALPRNMVITCQGSEDIRKLLESQGRRDIKLIDITLSKADSRKFENAVWDQFKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLDAKVLRVVLPRDMVFRTSTPKVVL
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    Tag-Free
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

引用文献

产品评价

靶点详情

  • 功能：
    Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
  • 亚细胞定位：
    Virion. Host cytoplasm.
  • 蛋白家族：
    Arenaviridae nucleocapsid protein family