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  4. Recombinant Human Zinc finger protein 467 (ZNF467)

Recombinant Human Zinc finger protein 467 (ZNF467)

  • 货号：
    CSB-YP026770HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP026770HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP026770HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP026770HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP026770HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ZNF467
  • Uniprot No.：
  • 别名：
    ZNF467; Zinc finger protein 467
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-595
  • 氨基酸序列
    MRETLEALSS LGFSVGQPEM APQSEPREGS HNAQEQMSSS REERALGVCS GHEAPTPEEG AHTEQAEAPC RGQACSAQKA QPVGTCPGEE WMIRKVKVED EDQEAEEEVE WPQHLSLLPS PFPAPDLGHL AAAYKLEPGA PGALSGLALS GWGPMPEKPY GCGECERRFR DQLTLRLHQR LHRGEGPCAC PDCGRSFTQR AHMLLHQRSH RGERPFPCSE CDKRFSKKAH LTRHLRTHTG ERPYPCAECG KRFSQKIHLG SHQKTHTGER PFPCTECEKR FRKKTHLIRH QRIHTGERPY QCAQCARSFT HKQHLVRHQR VHQTAGPARP SPDSSASPHS TAPSPTPSFP GPKPFACSDC GLSFGWKKNL ATHQCLHRSE GRPFGCDECA LGATVDAPAA KPLASAPGGP GCGPGSDPVV PQRAPSGERS FFCPDCGRGF SHGQHLARHP RVHTGERPFA CTQCDRRFGS RPNLVAHSRA HSGARPFACA QCGRRFSRKS HLGRHQAVHT GSRPHACAVC ARSFSSKTNL VRHQAIHTGS RPFSCPQCGK SFSRKTHLVR HQLIHGEAAH AAPDAALAAP AWSAPPEVAP PPLFF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a histone deacetylase complex.
  • 基因功能参考文献：
    1. ZNF467 gene DNA methylation is importants in the pathogenesis of idiopathic pulmonary fibrosis. PMID: 22700861
    2. These results identify EZI as a novel cargo protein for importin-7 and demonstrate a nucleocytoplasmic shuttling mechanism that is mediated by importin-7-dependent nuclear localization and CRM1-independent nuclear export. PMID: 17848547
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 数据库链接：

    HGNC: 23154

    OMIM: 614040

    KEGG: hsa:168544

    STRING: 9606.ENSP00000304769

    UniGene: Hs.726477