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  4. Recombinant Human Zinc finger protein 331 (ZNF331)

Recombinant Human Zinc finger protein 331 (ZNF331)

  • 货号：
    CSB-YP026680HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP026680HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP026680HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP026680HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP026680HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ZNF331
  • Uniprot No.：
  • 别名：
    C2H2 like zinc finger protein; C2H2 like zinc finger protein rearranged in thyroid adenomas; C2H2-like zinc finger protein rearranged in thyroid adenomas; DKFZp686L0787; KRAB zinc finger protein; OTTHUMP00000223038; OTTHUMP00000223039; OTTHUMP00000223040; OTTHUMP00000223041; OTTHUMP00000223042; OTTHUMP00000223043; OTTHUMP00000223045; OTTHUMP00000223046; OTTHUMP00000223047; OTTHUMP00000223048; OTTHUMP00000223052; OTTHUMP00000223053; OTTHUMP00000223054; RITA; Zinc finger protein 331; Zinc finger protein 361; Zinc finger protein 463; ZN331_HUMAN; ZNF331; ZNF361; ZNF463
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-463
  • 氨基酸序列
    MAQGLVTFAD VAIDFSQEEW ACLNSAQRDL YWDVMLENYS NLVSLDLESA YENKSLPTEK NIHEIRASKR NSDRRSKSLG RNWICEGTLE RPQRSRGRYV NQMIINYVKR PATREGTPPR THQRHHKENS FECKDCGKAF SRGYQLSQHQ KIHTGEKPYE CKECKKAFRW GNQLTQHQKI HTGEKPYECK DCGKAFRWGS SLVIHKRIHT GEKPYECKDC GKAFRRGDEL TQHQRFHTGE KDYECKDCGK TFSRVYKLIQ HKRIHSGEKP YECKDCGKAF ICGSSLIQHK RIHTGEKPYE CQECGKAFTR VNYLTQHQKI HTGEKPHECK ECGKAFRWGS SLVKHERIHT GEKPYKCTEC GKAFNCGYHL TQHERIHTGE TPYKCKECGK AFIYGSSLVK HERIHTGVKP YGCTECGKSF SHGHQLTQHQ KTHSGAKSYE CKECGKACNH LNHLREHQRI HNS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in transcriptional regulation. May play a role in spermatogenesis.
  • 基因功能参考文献：
    1. Data indicate that elevated levels of pretreatment RITA expression are correlated with unfavourable clinical outcome in anal carcinoma treated with concomitant chemoradiotherapy. PMID: 29122359
    2. Results show that ZNF331 is frequently methylated in human colorectal cancer, and the expression of ZNF331 is regulated by promoter region methylation. Methylation of ZNF331 is a poor prognostic marker of colorectal cancer. PMID: 29075358
    3. this study shows that ZNF331 gene may be associated with pathogenesis of asthma PMID: 27842724
    4. the present study provides initial evidence that RITA upregulates the expression level of IRE1a by increasing the stability of IRE1alpha mRNA in irradiated mtp53-expressing cervical cancer cells PMID: 26134873
    5. Methylation of ZNF331 Promotes Cell Invasion and Migration in Human Esophageal Cancer PMID: 25929867
    6. A high negative correlation between promoter DNA methylation and gene expression was observed for CDO1, ZNF331 and ZSCAN18 in gastrointestinal tumors. PMID: 24948044
    7. ZNF331 possesses important functions for the suppression of gastric carcinogenesis as a novel functional tumor-suppressor gene PMID: 22370639
    8. Unique expression of a 3.4-kbp transcript of ZNF331 is described in thyroid adenoma cell lines with 19q13 aberrations. PMID: 14610350

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Testis specific.
  • 数据库链接：

    HGNC: 15489

    OMIM: 606043

    KEGG: hsa:55422

    STRING: 9606.ENSP00000253144

    UniGene: Hs.185674