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  4. Recombinant Human WD and tetratricopeptide repeats protein 1 (WDTC1)

Recombinant Human WD and tetratricopeptide repeats protein 1 (WDTC1)

  • 中文名称：
    人WDTC1重组蛋白
  • 货号：
    CSB-YP822706HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人WDTC1重组蛋白
  • 货号：
    CSB-EP822706HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人WDTC1重组蛋白
  • 货号：
    CSB-EP822706HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人WDTC1重组蛋白
  • 货号：
    CSB-BP822706HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人WDTC1重组蛋白
  • 货号：
    CSB-MP822706HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    WDTC1
  • Uniprot No.：
  • 别名：
    WDTC1; KIAA1037; WD and tetratricopeptide repeats protein 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-677
  • 氨基酸序列
    MAKVNITRDL IRRQIKERGA LSFERRYHVT DPFIRRLGLE AELQGHSGCV NCLEWNEKGD LLASGSDDQH TIVWDPLHHK KLLSMHTGHT ANIFSVKFLP HAGDRILITG AADSKVHVHD LTVKETIHMF GDHTNRVKRI ATAPMWPNTF WSAAEDGLIR QYDLRENSKH SEVLIDLTEY CGQLVEAKCL TVNPQDNNCL AVGASGPFVR LYDIRMIHNH RKSMKQSPSA GVHTFCDRQK PLPDGAAQYY VAGHLPVKLP DYNNRLRVLV ATYVTFSPNG TELLVNMGGE QVYLFDLTYK QRPYTFLLPR KCHSSGEVQN GKMSTNGVSN GVSNGLHLHS NGFRLPESRG HVSPQVELPP YLERVKQQAN EAFACQQWTQ AIQLYSKAVQ RAPHNAMLYG NRAAAYMKRK WDGDHYDALR DCLKAISLNP CHLKAHFRLA RCLFELKYVA EALECLDDFK GKFPEQAHSS ACDALGRDIT AALFSKNDGE EKKGPGGGAP VRLRSTSRKD SISEDEMVLR ERSYDYQFRY CGHCNTTTDI KEANFFGSNA QYIVSGSDDG SFFIWEKETT NLVRVLQGDE SIVNCLQPHP SYCFLATSGI DPVVRLWNPR PESEDLTGRV VEDMEGASQA NQRRMNADPL EVMLLNMGYR ITGLSSGGAG ASDDEDSSEG QVQCRPS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • 基因功能参考文献：
    1. Our results identify a biochemical role for WDTC1 and extend the functional range of the CRL4 complex to the suppression of fat accumulation. PMID: 27113764
    2. High adp expression in human adipose tissue is associated with lower adiposity and enhanced glucose utilization. PMID: 23512946
    3. WDTC1 variation may be an important risk factor contributing to obesity in both Puerto Rican and white populations. PMID: 19238144
  • 数据库链接：

    HGNC: 29175

    KEGG: hsa:23038

    STRING: 9606.ENSP00000355317

    UniGene: Hs.469154