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  4. Recombinant Human Urotensin-2B (UTS2D)

Recombinant Human Urotensin-2B (UTS2D)

  • 货号：
    CSB-YP758825HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP758825HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP758825HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP758825HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP758825HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UTS2B
  • Uniprot No.：
  • 别名：
    MGC138371; Prepro URP; U-IIB; U2B; UIIB; urotensin 2 domain containing; Urotensin 2 domain containing protein; urotensin 2 related peptide; urotensin 2B; Urotensin II domain containing protein; urotensin II related peptide; Urotensin II-related peptide; Urotensin IIB; Urotensin-2 domain-containing protein; Urotensin-2B; URP; UTS2B; UTS2B_HUMAN; Uts2d
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    112-119
  • 氨基酸序列
    ACFWKYCV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potent vasoconstrictor.
  • 基因功能参考文献：
    1. family-based analysis of association between blood pressure, glomerular filtration and genes of the urotensin-II pathway (urotensin-II, urotensin-II related peptide, urotensin-II receptor) saturated with 28 tagging single nucleotide polymorphisms PMID: 24391740
    2. U2B'' has a relaxed specificity for its RNA targets. PMID: 21684671
    3. URP could possibly be the endogenous and functional ligand for the human UII receptor PMID: 14550283
    4. These findings suggest that U-II plays key roles in accelerating the development of atherosclerosis, thereby leading to coronary artery disease. PMID: 16940699
    5. Urotensin II gene may contribute to the genetic susceptibility to gestational diabetes mellitus in Chinese population PMID: 17327028
    6. Elevated serum urotensin II is associated with chronic liver disease and portal hypertension PMID: 17919235
    7. vascular remodelling processes in conjunction with enhanced vasoconstriction are involved in the pathogenesis of pulmonary hypertension; UII may play a novel role in the pathogenesis of this disorder PMID: 18000598

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Urotensin-2 family
  • 数据库链接：

    HGNC: 30894

    KEGG: hsa:257313

    STRING: 9606.ENSP00000340526

    UniGene: Hs.518492