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  4. Recombinant Human Uncharacterized protein CXorf21 (CXorf21)

Recombinant Human Uncharacterized protein CXorf21 (CXorf21)

  • 中文名称：
    Recombinant Human Uncharacterized protein CXorf21(CXorf21),Yeast
  • 货号：
    CSB-YP867184HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein CXorf21(CXorf21),Yeast
  • 货号：
    CSB-EP867184HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein CXorf21(CXorf21),Yeast
  • 货号：
    CSB-EP867184HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein CXorf21(CXorf21),Yeast
  • 货号：
    CSB-BP867184HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein CXorf21(CXorf21),Yeast
  • 货号：
    CSB-MP867184HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CXorf21
  • Uniprot No.：
  • 别名：
    CXorf21Protein CXorf21
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-301
  • 氨基酸序列
    MLSEGYLSGL EYWNDIHWSC ASYNEQVAGE KEEETNSVAT LSYSSVDETQ VRSLYVSCKS SGKFISSVHS RESQHSRSQR VTVLQTNPNP VFESPNLAAV EICRDASRET YLVPSSCKSI CKNYNDLQIA GGQVMAINSV TTDFPSESSF EYGPLLKSSE IPLPMEDSIS TQPSDFPQKP IQRYSSYWRI TSIKEKSSLQ MQNPISNAVL NEYLEQKVVE LYKQYIMDTV FHDSSPTQIL ASELIMTSVD QISLQVSREK NLETSKARDI VFSRLLQLMS TEITEISTPS LHISQYSNVN P
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to IRF5 activation and subsequent expression of type I interferons. Plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes.
  • 亚细胞定位：
    Lysosome membrane. Endosome membrane. Nucleus. Cytoplasm.
  • 组织特异性：
    Highly expressed in immune cell types such as B-cells, neutrophils, dendritic cells and monocytes, the expression levels are two-three-fold higher in female cells compared to male cells (at protein level). Expressed at low levels in T-cells and NK cells.
  • 数据库链接：

    HGNC: 25667

    KEGG: hsa:80231

    STRING: 9606.ENSP00000368245

    UniGene: Hs.665009