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  4. Recombinant Human Transmembrane protein 8C (TMEM8C), partial

Recombinant Human Transmembrane protein 8C (TMEM8C), partial

  • 中文名称：
    人MYMK重组蛋白
  • 货号：
    CSB-YP407391HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MYMK重组蛋白
  • 货号：
    CSB-EP407391HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MYMK重组蛋白
  • 货号：
    CSB-EP407391HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MYMK重组蛋白
  • 货号：
    CSB-BP407391HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MYMK重组蛋白
  • 货号：
    CSB-MP407391HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MYMK
  • Uniprot No.：
  • 别名：
    MYMK; TMEM226; TMEM8C; Protein myomaker; Myoblast fusion maker; Transmembrane protein 226; Transmembrane protein 8C
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. Actively participates in the membrane fusion reaction by mediating the mixing of cell membrane lipids (hemifusion) upstream of MYMX. Acts independently of MYMX. Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers. Also involved in skeletal muscle hypertrophy, probably by mediating the fusion of satellite cells with myofibers.
  • 基因功能参考文献：
    1. The data establish that MYMK activity is necessary for normal muscle development and maintenance in humans and zebrafish, and expand the spectrum of congenital myopathies to include cell-cell fusion deficits. PMID: 28681861
  • 相关疾病：
    Carey-Fineman-Ziter syndrome (CFZS)
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TMEM8 family
  • 数据库链接：

    HGNC: 33778

    OMIM: 254940

    KEGG: hsa:389827

    UniGene: Hs.512467