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Recombinant Human Torsin-1B (TOR1B)

  • 中文名称：
    人TOR1B重组蛋白
  • 货号：
    CSB-YP024070HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TOR1B重组蛋白
  • 货号：
    CSB-EP024070HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TOR1B重组蛋白
  • 货号：
    CSB-EP024070HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TOR1B重组蛋白
  • 货号：
    CSB-BP024070HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TOR1B重组蛋白
  • 货号：
    CSB-MP024070HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TOR1B
  • Uniprot No.：
  • 别名：
    TOR1B; DQ1; FKSG18; Torsin-1B; Torsin ATPase-1B; EC 3.6.4.-; Torsin family 1 member B
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    25-336
  • 氨基酸序列
    FEPITV GLAIGAASAI TGYLSYNDIY CRFAECCREE RPLNASALKL DLEEKLFGQH LATEVIFKAL TGFRNNKNPK KPLTLSLHGW AGTGKNFVSQ IVAENLHPKG LKSNFVHLFV STLHFPHEQK IKLYQDQLQK WIRGNVSACA NSVFIFDEMD KLHPGIIDAI KPFLDYYEQV DGVSYRKAIF IFLSNAGGDL ITKTALDFWR AGRKREDIQL KDLEPVLSVG VFNNKHSGLW HSGLIDKNLI DYFIPFLPLE YRHVKMCVRA EMRARGSAID EDIVTRVAEE MTFFPRDEKI YSDKGCKTVQ SRLDFH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues.
  • 基因功能参考文献：
    1. the induction of a conditional, dominant-negative TorsinB variant provokes a profound reorganization of the endomembrane system into foci containing double membrane structures that are derived from the ER. PMID: 24275647
    2. torsinB is needed for developmental events occurring in the early postnatal phase and is necessary for functional activity throughout life PMID: 16938275
  • 亚细胞定位：
    Endoplasmic reticulum lumen. Nucleus membrane.
  • 蛋白家族：
    ClpA/ClpB family, Torsin subfamily
  • 组织特异性：
    Widely expressed with low levels in brain.
  • 数据库链接：

    HGNC: 11995

    OMIM: 608050

    KEGG: hsa:27348

    STRING: 9606.ENSP00000259339

    UniGene: Hs.252682