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  4. Recombinant Human Sperm equatorial segment protein 1 (SPESP1)

Recombinant Human Sperm equatorial segment protein 1 (SPESP1)

  • 货号：
    CSB-YP022533HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP022533HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP022533HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP022533HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP022533HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SPESP1
  • Uniprot No.：
  • 别名：
    Equatorial segment protein; ESP; Glycosylated 38 kDa sperm protein C 7/8; Glycosylated 38 kDa sperm protein C-7/8; MGC24663; SP-ESP; Sperm equatorial segment protein 1; Sperm equatorial segment protein 1 precursor; SPESP; SPESP_HUMAN; Spesp1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-350
  • 氨基酸序列
    Y PSITVTPDEE QNLNHYIQVL ENLVRSVPSG EPGREKKSNS PKHVYSIASK GSKFKELVTH GDASTENDVL TNPISEETTT FPTGGFTPEI GKKKHTESTP FWSIKPNNVS IVLHAEEPYI ENEEPEPEPE PAAKQTEAPR MLPVVTESST SPYVTSYKSP VTTLDKSTGI GISTESEDVP QLSGETAIEK PEEFGKHPES WNNDDILKKI LDINSQVQQA LLSDTSNPAY REDIEASKDH LKRSLALAAA AEHKLKTMYK SQLLPVGRTS NKIDDIETVI NMLCNSRSKL YEYLDIKCVP PEMREKAATV FNTLKNMCRS RRVTALLKVY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in fertilization ability of sperm.
  • 基因功能参考文献：
    1. Equatorial segment protein (ESP), a novel 349-amino acid concanavalin-A-binding protein encoded by a two-exon gene (SP-ESP) located on chromosome 15 at q22, has been localized to the equatorial segment of ejaculated human sperm. PMID: 12773409
    2. human alloantigen involved in sperm-egg binding and fusion PMID: 17978344
  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族：
    SPESP1 family
  • 组织特异性：
    Highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly expressed in placenta and fetal lung.
  • 数据库链接：

    HGNC: 15570

    OMIM: 609399

    KEGG: hsa:246777

    STRING: 9606.ENSP00000312284

    UniGene: Hs.657932