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  4. Recombinant Human Solute carrier organic anion transporter family member 4A1 (SLCO4A1), partial

Recombinant Human Solute carrier organic anion transporter family member 4A1 (SLCO4A1), partial

  • 中文名称：
    人SLCO4A1重组蛋白
  • 货号：
    CSB-YP822181HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLCO4A1重组蛋白
  • 货号：
    CSB-EP822181HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLCO4A1重组蛋白
  • 货号：
    CSB-EP822181HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLCO4A1重组蛋白
  • 货号：
    CSB-BP822181HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLCO4A1重组蛋白
  • 货号：
    CSB-MP822181HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLCO4A1
  • Uniprot No.：
  • 别名：
    Colon organic anion transporter; OATP-E; OATP-RP1; OATP1; OATP4A1; OATPE; OATPRP1; Organic anion transporter polypeptide-related protein 1; Organic anion-transporting polypeptide E; POAT; SLC21A12; Slco4a1; SO4A1_HUMAN; Sodium-independent organic anion transporter E; Solute carrier family 21 (organic anion transporter) member 12; Solute carrier family 21 member 12; Solute carrier organic anion transporter family member 4A1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate.
  • 基因功能参考文献：
    1. SLCO4A1 may be a valuable marker of poor prognostic for colorectal cancer (CRC). Furthermore, SLCO4A1 plays an important role in CRC cell proliferation, migration, invasion, and carcinogenesis PMID: 28378090
    2. our results revealed altered OATP3A1 and OATP4A1 mRNA levels and novel mechanisms that might be involved in their regulation in colorectal cancer PMID: 26349991
    3. High OATP4A1 expression is associated with small cell lung cancer. PMID: 25301452
    4. oligomerization of Oatp1a1 with PDZK1 is critical for its proper subcellular localization and function PMID: 15994332
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Organo anion transporter (TC 2.A.60) family
  • 组织特异性：
    Ubiquitous, with the exception of spleen and leukocytes.
  • 数据库链接：

    HGNC: 10953

    OMIM: 612436

    KEGG: hsa:28231

    STRING: 9606.ENSP00000217159

    UniGene: Hs.235782