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  4. Recombinant Human SLIT and NTRK-like protein 6 (SLITRK6), partial

Recombinant Human SLIT and NTRK-like protein 6 (SLITRK6), partial

  • 中文名称：
    人SLITRK6重组蛋白
  • 货号：
    CSB-YP867155HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLITRK6重组蛋白
  • 货号：
    CSB-EP867155HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLITRK6重组蛋白
  • 货号：
    CSB-EP867155HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLITRK6重组蛋白
  • 货号：
    CSB-BP867155HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLITRK6重组蛋白
  • 货号：
    CSB-MP867155HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    4832410J21Rik; DFNMYP; MGC119595; MGC119596; MGC119597; OTTHUMP00000066012; SLIK6_HUMAN; SLIT and NTRK like family member 6; SLIT and NTRK like protein 6; SLIT and NTRK-like protein 6; Slit and trk like 6; Slit and trk like gene 6; SLITRK 6; Slitrk6
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulator of neurite outgrowth required for normal hearing and vision.
  • 基因功能参考文献：
    1. Analysis of two exons of SLITRK6 gene in a Moroccan family identify a novel single deleterious mutation c.696delG, p.Trp232Cysfs*10 at homozygous state in the exon 2 of the SLITRK6, a gene reported to cause deafness and myopia in various populations. PMID: 29551497
    2. Human cytomegalovirus downregulates SLITRK6 expression through IE2. PMID: 27530937
    3. SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans. PMID: 23946138
    4. SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness. PMID: 23543054
  • 相关疾病：
    Deafness and myopia (DFNMYP)
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    SLITRK family
  • 组织特异性：
    In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
  • 数据库链接：

    HGNC: 23503

    OMIM: 221200

    KEGG: hsa:84189

    STRING: 9606.ENSP00000383143

    UniGene: Hs.525105