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  4. Recombinant Human Psoriasis susceptibility 1 candidate gene 2 protein (PSORS1C2)

Recombinant Human Psoriasis susceptibility 1 candidate gene 2 protein (PSORS1C2)

  • 中文名称：
    人PSORS1C2重组蛋白
  • 货号：
    CSB-YP883430HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PSORS1C2重组蛋白
  • 货号：
    CSB-EP883430HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PSORS1C2重组蛋白
  • 货号：
    CSB-EP883430HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PSORS1C2重组蛋白
  • 货号：
    CSB-BP883430HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PSORS1C2重组蛋白
  • 货号：
    CSB-MP883430HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PSORS1C2
  • Uniprot No.：
  • 别名：
    PSORS1C2; C6orf17; SPR1; Psoriasis susceptibility 1 candidate gene 2 protein; Protein SPR1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    23-136
  • 氨基酸序列
    SEGHPSHP PAEDREEAGS PTLPQGPPVP GDPWPGAPPL FEDPPPTRPS RPWRDLPETG VWLPEPPRTD PPQPPRPDDP WPAGPQPPEN PWPPAPEVDN RPQEEPDLDP PREEYR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. In summary, our results identify PSORS1C2 as a keratinocyte cornification-associated protein that has originated in evolutionarily basal mammals and has undergone gene inactivation in association with the loss of the skin barrier function in aquatic mammals. PMID: 27943452
    2. In Czech population, association between HLA-Cw*06 and psoriatic arthritis was low and restricted to psoriatic arthritis patients with early psoriasis onset PMID: 22821332
    3. HLA-Cw6 remains the major risk allele in Chinese psoriatics, and that the SPR1 gene might not play an important role in the causation of PV. PMID: 12823445
    4. HLA-Cw*06 allele frequency is associated with psoriasis PMID: 15523160
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Expressed in skin. Also expressed in heart and skeletal muscle.
  • 数据库链接：

    HGNC: 17199

    OMIM: 613526

    KEGG: hsa:170680

    STRING: 9606.ENSP00000259845

    UniGene: Hs.146824