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  4. Recombinant Human Protein spire homolog 2 (SPIRE2)

Recombinant Human Protein spire homolog 2 (SPIRE2)

  • 中文名称：
    人SPIRE2重组蛋白
  • 货号：
    CSB-YP855490HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SPIRE2重组蛋白
  • 货号：
    CSB-EP855490HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SPIRE2重组蛋白
  • 货号：
    CSB-EP855490HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SPIRE2重组蛋白
  • 货号：
    CSB-BP855490HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SPIRE2重组蛋白
  • 货号：
    CSB-MP855490HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SPIRE2
  • Uniprot No.：
  • 别名：
    MGC117166; Protein spire homolog 2; Spir-2; SPIR2_HUMAN; Spire homolog 2 (Drosophila); SPIRE2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-714
  • 氨基酸序列
    MARAGSCGGA AAGAGRPEPW ELSLEEVLKA YEQPLNEEQA WAVCFQGCRG LRGSPGRRLR DTGDLLLRGD GSVGAREPEA AEPATMVVPL ASSEAQTVQS LGFAIYRALD WGLDESEERE LSPQLERLID LMANNDSEDS GCGAADEGYG GPEEEEEAEG VPRSVRTFAQ AMRLCAARLT DPRGAQAHYQ AVCRALFVET LELRAFLARV REAKEMLQKL REDEPHLETP RAELDSLGHT DWARLWVQLM RELRRGVKLK KVQEQEFNPL PTEFQLTPFE MLMQDIRARN YKLRKVMVDG DIPPRVKKDA HELILDFIRS RPPLKQVSER RLRPLPPKQR SLHEKILEEI KQERRLRPVR GEGWAARGFG SLPCILNACS GDAKSTSCIN LSVTDAGGSA QRPRPRVLLK APTLAEMEEM NTSEEEESPC GEVTLKRDRS FSEHDLAQLR SEVASGLQSA THPPGGTEPP RPRAGSAHVW RPGSRDQGTC PASVSDPSHP LLSNRGSSGD RPEASMTPDA KHLWLEFSHP VESLALTVEE VMDVRRVLVK AEMEKFLQNK ELFSSLKKGK ICCCCRAKFP LFSWPPSCLF CKRAVCTSCS IKMKMPSKKF GHIPVYTLGF ESPQRVSAAK TAPIQRRDIF QSLQGPQWQS VEEAFPHIYS HGCVLKDVCS ECTSFVADVV RSSRKSVDVL NTTPRRSRQT QSLYIPNTRT LDFK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage.
  • 基因功能参考文献：
    1. influences intracellular replication of Salmonella typhimurium PMID: 27627128
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Spire family
  • 数据库链接：

    HGNC: 30623

    OMIM: 609217

    KEGG: hsa:84501

    STRING: 9606.ENSP00000367494

    UniGene: Hs.461786