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  4. Recombinant Human Protein lunapark (LNP), partial

Recombinant Human Protein lunapark (LNP), partial

  • 中文名称：
    人LNPK重组蛋白
  • 货号：
    CSB-YP883656HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人LNPK重组蛋白
  • 货号：
    CSB-EP883656HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人LNPK重组蛋白
  • 货号：
    CSB-EP883656HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人LNPK重组蛋白
  • 货号：
    CSB-BP883656HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人LNPK重组蛋白
  • 货号：
    CSB-MP883656HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    LNPK
  • Uniprot No.：
  • 别名：
    lnp; LNP_HUMAN; Protein lunapark
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb development. Is involved in central nervous system development.
  • 基因功能参考文献：
    1. Despite its interaction with gp78, Lnp does not seem to have a broad function in degradation of misfolded ER proteins. PMID: 27387505
    2. used live cell imaging to show that mammalian Lnp1 affects endoplasmic reticulum junction mobility and hence network dynamics PMID: 25548161
    3. Protein N-myristoylation plays a critical role in the endoplasmic reticulum morphological change induced by overexpression of protein Lunapark. PMID: 24223779
    4. Propose that Lnp1p and Sey1p act antagonistically to balance endoplasmic reticular polygonal network formation. PMID: 22729086
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Lunapark family
  • 组织特异性：
    Expressed in neural precursor cells, where it is detected at the growth-cone-like structure and branching sites of neurite-like processes.
  • 数据库链接：

    HGNC: 21610

    OMIM: 610236

    KEGG: hsa:80856

    STRING: 9606.ENSP00000272748

    UniGene: Hs.209561