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  4. Recombinant Human Protein FAM92A1 (FAM92A1)

Recombinant Human Protein FAM92A1 (FAM92A1)

  • 中文名称：
    人FAM92A重组蛋白
  • 货号：
    CSB-YP008396HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人FAM92A重组蛋白
  • 货号：
    CSB-EP008396HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人FAM92A重组蛋白
  • 货号：
    CSB-EP008396HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人FAM92A重组蛋白
  • 货号：
    CSB-BP008396HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人FAM92A重组蛋白
  • 货号：
    CSB-MP008396HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    FAM92A
  • Uniprot No.：
  • 别名：
    FAM92A; FAM92A1Protein FAM92A
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-289
  • 氨基酸序列
    MMRRTLENRN AQTKQLQTAV SNVEKHFGEL CQIFAAYVRK TARLRDKADL LVNEINAYAA TETPHLKLGL MNFADEFAKL QDYRQAEVER LEAKVVEPLK TYGTIVKMKR DDLKATLTAR NREAKQLTQL ERTRQRNPSD RHVISQAETE LQRAAMDASR TSRHLEETIN NFERQKMKDI KTIFSEFITI EMLFHGKALE VYTAAYQNIQ NIDEDEDLEV FRNSLYAPDY SSRLDIVRAN SKSPLQRSLS AKCVSGTGQV STCRLRKDQQ AEDDEDDELD VTEEENFLK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a positive regulator of ciliary hedgehog signaling. Probable regulator of ciliogenesis involved in limb morphogenesis. In cooperation with CBY1 it is involved in the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis.
  • 基因功能参考文献：
    1. FAM92 proteins interact with Cby1 to promote ciliogenesis via regulation of membrane-remodeling processes. PMID: 27528616
    2. FAM92A1-289 retains many oncogenic properties evidenced by facilitating cell migration, boosting cell proliferation and promoting colony formation in vitro and tumor growth in vivo, providing evidence for use as as a therapeutic target for cancer treatment. PMID: 27798880
    3. FAM92A1 has different splicing variants, and that it may take part in regulating cell proliferation and apoptosis. PMID: 17646714
    4. FAM92A1-289 is a new tumor-related gene with oncogenic potentials to probably play roles in renal carcinogenesis. PMID: 19059705
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium.; [Isoform 3]: Nucleus.
  • 蛋白家族：
    FAM92 family
  • 数据库链接：

    HGNC: 30452

    OMIM: 617273

    KEGG: hsa:137392

    UniGene: Hs.125038