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  4. Recombinant Human Nuclear apoptosis-inducing factor 1 (NAIF1)

Recombinant Human Nuclear apoptosis-inducing factor 1 (NAIF1)

  • 货号：
    CSB-YP715122HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP715122HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP715122HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP715122HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP715122HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NAIF1
  • Uniprot No.：
  • 别名：
    bA379C10.2; C9orf90; chromosome 9 open reading frame 90; Naif1; NAIF1_HUMAN; Nuclear apoptosis-inducing factor 1; RP11-379C10.2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-327
  • 氨基酸序列
    MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG GGSGGGGPAV APVLLTPMQQ RICNLLGEAT IISLPSTTEI HPVALGPSAT AAAATVTLTQ IPTETTYHTL EEGVVEYCTA EAPPPLPPET PVDMMAQHAD TSVKPQALKS RIALNSAKLI QEQRVTNLHV KEIAQHLEQQ NDLLQMIRRS QEVQACAQER QAQAMEGTQA ALSVLIQVLR PMIKDFRRYL QSNTANPAPA SDPGQVAQNG QPDSIIQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Induces apoptosis.
  • 基因功能参考文献：
    1. MiR-24 acted as an oncomir, at least partially through regulation of its functional target NAIF1 in non-small cell lung cancer. PMID: 25725584
    2. NAIF1 plays a role in regulating cellular migration and invasion through the MAPK pathways and may function as a tumor suppressor in the progression of gastric carcinoma. PMID: 25432142
    3. NAIF1 is down-regulated in gastric cancer. PMID: 21286669
    4. NAIF1 (C9orf90)is a nuclear protein that induces apoptosis when overexpressed PMID: 16378748
    5. The functions of two transposon-derived human proteins: HARBI1, a domesticated transposase-derived protein, and NAIF1, which contains a trihelix motif similar to that described in the Myb-like protein, was investigated. PMID: 18339812

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    NAIF1 family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 25446

    OMIM: 610673

    KEGG: hsa:203245

    STRING: 9606.ENSP00000362170

    UniGene: Hs.373606