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  4. Recombinant Human Major facilitator superfamily domain-containing protein 2B (MFSD2B), partial

Recombinant Human Major facilitator superfamily domain-containing protein 2B (MFSD2B), partial

  • 中文名称：
    人MFSD2B重组蛋白
  • 货号：
    CSB-YP407092HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MFSD2B重组蛋白
  • 货号：
    CSB-EP407092HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MFSD2B重组蛋白
  • 货号：
    CSB-EP407092HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MFSD2B重组蛋白
  • 货号：
    CSB-BP407092HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MFSD2B重组蛋白
  • 货号：
    CSB-MP407092HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MFSD2B
  • Uniprot No.：
  • 别名：
    Major facilitator superfamily domain-containing protein 2B; MFS2B_HUMAN; Mfsd2b
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology. Does not transport lysophosphatidylcholine (LPC).
  • 基因功能参考文献：
    1. S1P secretion by Mfsd2b is critical for red blood cell morphology; data reveal an unexpected physiological role of red blood cells in sphingolipid metabolism in circulation; findings open new avenues for investigating the signalling roles of S1P derived from red blood cells and platelets PMID: 29045386
    2. MFSD2B, CCL20 and STAT1, or STARD7 and ZNF512 genes may be risk or protect factors in prognosis of ADC; HTR2B, DPP4, and TGFBRAP1 genes may be risk factors in prognosis of SQC. PMID: 27301951
    3. Results identify Mfsd2a (major facilitator superfamily domain-containing protein 2a) and an additional closely related protein Mfsd2b, and suggest that Mfsd2a plays a role in adaptive thermogenesis. PMID: 18694395
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily
  • 数据库链接：

    HGNC: 37207

    OMIM: 617845

    KEGG: hsa:388931

    STRING: 9606.ENSP00000385527

    UniGene: Hs.407482