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  4. Recombinant Human Large subunit GTPase 1 homolog (LSG1)

Recombinant Human Large subunit GTPase 1 homolog (LSG1)

  • 中文名称：
    人LSG1重组蛋白
  • 货号：
    CSB-YP861981HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人LSG1重组蛋白
  • 货号：
    CSB-EP861981HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人LSG1重组蛋白
  • 货号：
    CSB-EP861981HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人LSG1重组蛋白
  • 货号：
    CSB-BP861981HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人LSG1重组蛋白
  • 货号：
    CSB-MP861981HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    LSG1
  • Uniprot No.：
  • 别名：
    LSG1; Large subunit GTPase 1 homolog; hLsg1; EC 3.6.1.-
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-658
  • 氨基酸序列
    MGRRRAPAGG SLGRALMRHQ TQRSRSHRHT DSWLHTSELN DGYDWGRLNL QSVTEQSSLD DFLATAELAG TEFVAEKLNI KFVPAEARTG LLSFEESQRI KKLHEENKQF LCIPRRPNWN QNTTPEELKQ AEKDNFLEWR RQLVRLEEEQ KLILTPFERN LDFWRQLWRV IERSDIVVQI VDARNPLLFR CEDLECYVKE MDANKENVIL INKADLLTAE QRSAWAMYFE KEDVKVIFWS ALAGAIPLNG DSEEEANRDD RQSNTTKFGH SSFDQAEISH SESEHLPARD SPSLSENPTT DEDDSEYEDC PEEEEDDWQT CSEEDGPKEE DCSQDWKESS TADSEARSRK TPQKRQIHNF SHLVSKQELL ELFKELHTGR KVKDGQLTVG LVGYPNVGKS STINTIMGNK KVSVSATPGH TKHFQTLYVE PGLCLCDCPG LVMPSFVSTK AEMTCSGILP IDQMRDHVPP VSLVCQNIPR HVLEATYGIN IITPREDEDP HRPPTSEELL TAYGYMRGFM TAHGQPDQPR SARYILKDYV SGKLLYCHPP PGRDPVTFQH QHQRLLENKM NSDEIKMQLG RNKKAKQIEN IVDKTFFHQE NVRALTKGVQ AVMGYKPGSG VVTASTASSE NGAGKPWKKH GNRNKKEKSR RLYKHLDM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).
  • 基因功能参考文献：
    1. hLsg1 is an essential GTPase predominantly located in the endoplasmic reticulum and, in some cells, in Cajal bodies in the nucleus. PMID: 16209721
  • 亚细胞定位：
    Cytoplasm. Endoplasmic reticulum. Nucleus, Cajal body. Note=Shuttles between the Cajal bodies in the nucleus and the endoplasmic reticulum.
  • 蛋白家族：
    TRAFAC class YlqF/YawG GTPase family, LSG1 subfamily
  • 数据库链接：

    HGNC: 25652

    OMIM: 610780

    KEGG: hsa:55341

    STRING: 9606.ENSP00000265245

    UniGene: Hs.744061