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  4. Recombinant Human LYR motif-containing protein 7 (LYRM7)

Recombinant Human LYR motif-containing protein 7 (LYRM7)

  • 中文名称：
    人LYRM7重组蛋白
  • 货号：
    CSB-YP725940HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人LYRM7重组蛋白
  • 货号：
    CSB-EP725940HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人LYRM7重组蛋白
  • 货号：
    CSB-EP725940HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人LYRM7重组蛋白
  • 货号：
    CSB-BP725940HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人LYRM7重组蛋白
  • 货号：
    CSB-MP725940HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    LYRM7
  • Uniprot No.：
  • 别名：
    LYRM7; C5orf31; MZM1LComplex III assembly factor LYRM7; LYR motif-containing protein 7
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-104
  • 氨基酸序列
    MGRAVKVLQL FKTLHRTRQQ VFKNDARALE AARIKINEEF KNNKSETSSK KIEELMKIGS DVELLLRTSV IQGIHTDHNT LKLVPRKDLL VENVPYCDAP TQKQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
  • 基因功能参考文献：
    1. The s identified homozygosity for a splice site destroying 4 base pair deletion in LYRM7 in a child with recurrent lactic acidotic crises and distinct early-onset leukencephalopathy. PMID: 28694194
    2. In multifocal cavitating leukoencephalopathy patients, LYRm7 mutations were identified associated with distinct MRI appearances. PMID: 26912632
    3. LYRM7/MZM1L is a novel disease gene, causing cIII-defective, early onset, severe mitochondrial encephalopathy. PMID: 24014394
  • 相关疾病：
    Mitochondrial complex III deficiency, nuclear 8 (MC3DN8)
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Complex I LYR family
  • 数据库链接：

    HGNC: 28072

    OMIM: 615831

    KEGG: hsa:90624

    STRING: 9606.ENSP00000368688

    UniGene: Hs.115467