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  4. Recombinant Human Kelch-like protein 31 (KLHL31)

Recombinant Human Kelch-like protein 31 (KLHL31)

  • 中文名称：
    人KLHL31重组蛋白
  • 货号：
    CSB-YP875676HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人KLHL31重组蛋白
  • 货号：
    CSB-EP875676HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人KLHL31重组蛋白
  • 货号：
    CSB-EP875676HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人KLHL31重组蛋白
  • 货号：
    CSB-BP875676HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人KLHL31重组蛋白
  • 货号：
    CSB-MP875676HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    KLHL31
  • Uniprot No.：
  • 别名：
    KLHL31; BKLHD6; KBTBD1; KLHL; Kelch-like protein 31; BTB and kelch domain-containing protein 6; Kelch repeat and BTB domain-containing protein 1; Kelch-like protein KLHL
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-634
  • 氨基酸序列
    APKKKIVKK NKGDINEMTI IVEDSPLNKL NALNGLLEGG NGLSCISSEL TDASYGPNLL EGLSKMRQEN FLCDLVIGTK TKSFDVHKSV MASCSEYFYN ILKKDPSIQR VDLNDISPLG LATVIAYAYT GKLTLSLYTI GSIISAAVYL QIHTLVKMCS DFLIREMSVE NCMYVVNIAE TYSLKNAKAA AQKFIRDNFL EFAESDQFMK LTFEQINELL IDDDLQLPSE IVAFQIAMKW LEFDQKRVKY AADLLSNIRF GTISAQDLVN YVQSVPRMMQ DADCHRLLVD AMNYHLLPYH QNTLQSRRTR IRGGCRVLVT VGGRPGLTEK SLSRDILYRD PENGWSKLTE MPAKSFNQCV AVMDGFLYVA GGEDQNDARN QAKHAVSNFC RYDPRFNTWI HLASMNQKRT HFSLSVFNGL VYAAGGRNAE GSLASLECYV PSTNQWQPKT PLEVARCCHA SAVADGRVLV TGGYIANAYS RSVCAYDPAS DSWQELPNLS TPRGWHCAVT LSDRVYVMGG SQLGPRGERV DVLTVECYSP ATGQWSYAAP LQVGVSTAGV SALHGRAYLV GGWNEGEKKY KKCIQCFSPE LNEWTEDDEL PEATVGVSCC TLSMPNNVTR ESRASSVSSV PVSI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).
  • 基因功能参考文献：
    1. These results suggest that KLHL31 protein may act as a new transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. PMID: 18719355
  • 组织特异性：
    Strongly expressed in skeletal muscle and weakly in heart. According to PubMed:15302408, not expressed in other tissues. According to PubMed:18719355, abundantly expressed in both embryonic skeletal and heart tissues.
  • 数据库链接：

    HGNC: 21353

    OMIM: 610749

    KEGG: hsa:401265

    STRING: 9606.ENSP00000359942

    UniGene: Hs.131064