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  4. Recombinant Human Gamma-taxilin (TXLNG)

Recombinant Human Gamma-taxilin (TXLNG)

  • 中文名称：
    人TXLNG重组蛋白
  • 货号：
    CSB-YP865141HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TXLNG重组蛋白
  • 货号：
    CSB-EP865141HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TXLNG重组蛋白
  • 货号：
    CSB-EP865141HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TXLNG重组蛋白
  • 货号：
    CSB-BP865141HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TXLNG重组蛋白
  • 货号：
    CSB-MP865141HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TXLNG
  • Uniprot No.：
  • 别名：
    chromosome X open reading frame 15; CXorf15; Environmental lipopolysaccharide-responding gene protein; factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription; Factor inhibiting ATF4-mediated transcription; FIAT; Gamma-taxilin; Lipopolysaccharide-specific response protein 5; LSR5; TXLNG; TXLNG_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-528
  • 氨基酸序列
    MATRVEEAAR GRGGGAEEAT EAGRGGRRRS PRQKFEIGTM EEAGICGLGV KADMLCNSQS NDILQHQGSN CGGTSNKHSL EEDEGSDFIT ENRNLVSPAY CTQESREEIP GGEARTDPPD GQQDSECNRN KEKTLGKEVL LLMQALNTLS TPEEKLAALC KKYADLLEES RSVQKQMKIL QKKQAQIVKE KVHLQSEHSK AILARSKLES LCRELQRHNK TLKEENMQQA REEEERRKEA TAHFQITLNE IQAQLEQHDI HNAKLRQENI ELGEKLKKLI EQYALREEHI DKVFKHKELQ QQLVDAKLQQ TTQLIKEADE KHQREREFLL KEATESRHKY EQMKQQEVQL KQQLSLYMDK FEEFQTTMAK SNELFTTFRQ EMEKMTKKIK KLEKETIIWR TKWENNNKAL LQMAEEKTVR DKEYKALQIK LERLEKLCRA LQTERNELNE KVEVLKEQVS IKAAIKAANR DLATPVMQPC TALDSHKELN TSSKRALGAH LEAEPKSQRS AVQKPPSTGS APAIESVD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression.
  • 基因功能参考文献：
    1. Taken together with the result that gamma-taxilin protein expression levels were decreased at the onset of mitosis, we propose that gamma-taxilin participates in Nek2A-mediated centrosome disjunction as a negative regulator through its interaction with Nek2A. PMID: 29225051
    2. [review] First evidence of a functional interaction between ATF4, FIAT (factor-inhibiting ATF4-mediated transcription) and alphaNAC (nascent polypeptide-associated complex and coactivator alpha). PMID: 22082360
    3. identification of isoforms of taxilin; interaction with syntaxin; tissue distribution [beta-taxilin, gamma-taxilin]. PMID: 15184072
    4. evaluation of the effects of a novel environmental lipopolysaccharide-responding (Elrg) gene on the regulation of proliferation and cell cycle of the hepatoma-derived cell line, HepG2 PMID: 18068885
  • 亚细胞定位：
    Nucleus membrane. Cytoplasm, cytosol.
  • 蛋白家族：
    Taxilin family
  • 组织特异性：
    Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.
  • 数据库链接：

    HGNC: 18578

    OMIM: 300677

    KEGG: hsa:55787

    STRING: 9606.ENSP00000369465

    UniGene: Hs.555961