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  4. Recombinant Human GATA zinc finger domain-containing protein 1 (GATAD1)

Recombinant Human GATA zinc finger domain-containing protein 1 (GATAD1)

  • 中文名称：
    人GATAD1重组蛋白
  • 货号：
    CSB-YP851967HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人GATAD1重组蛋白
  • 货号：
    CSB-EP851967HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人GATAD1重组蛋白
  • 货号：
    CSB-EP851967HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人GATAD1重组蛋白
  • 货号：
    CSB-BP851967HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人GATAD1重组蛋白
  • 货号：
    CSB-MP851967HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    GATAD1
  • Uniprot No.：
  • 别名：
    GATAD1; ODAG; GATA zinc finger domain-containing protein 1; Ocular development-associated gene protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-269
  • 氨基酸序列
    MPLGLKPTCS VCKTTSSSMW KKGAQGEILC HHCTGRGGAG SGGAGSGAAG GTGGSGGGGF GAATFASTSA TPPQSNGGGG GKQSKQEIHR RSARLRNTKY KSAPAAEKKV STKGKGRRHI FKLKNPIKAP ESVSTIITAE SIFYKGVYYQ IGDVVSVIDE QDGKPYYAQI RGFIQDQYCE KSAALTWLIP TLSSPRDQFD PASYIIGPEE DLPRKMEYLE FVCHAPSEYF KSRSSPFPTV PTRPEKGYIW THVGPTPAIT IKESVANHL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
  • 基因功能参考文献：
    1. GATAD1 plays a pivotal oncogenic role in hepatocellular carcinoma by directly inducing PRL3 transcription to activate the Akt signaling pathway. GATAD1 may serve as an independent poor prognostic factor for hepatocellular carcinoma patients PMID: 29266303
    2. GATAD1 expression was significantly decreased in the third-trimester placentas associated with preeclampsia than those associated with normal pregnancy. PMID: 24462704
    3. GATAD1 mutation is associated with autosomal recessive dilated cardiomyopathy. PMID: 21965549
  • 相关疾病：
    Cardiomyopathy, dilated 2B (CMD2B)
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes.
  • 数据库链接：

    HGNC: 29941

    OMIM: 614518

    KEGG: hsa:57798

    STRING: 9606.ENSP00000287957

    UniGene: Hs.21145