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  4. Recombinant Human G kinase-anchoring protein 1 (GKAP1)

Recombinant Human G kinase-anchoring protein 1 (GKAP1)

  • 货号：
    CSB-YP719617HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP719617HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP719617HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP719617HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP719617HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    GKAP1
  • Uniprot No.：
  • 别名：
    cGMP dependent protein kinase anchoring protein 42kDa; cGMP dependent protein kinase anchoring protein of 42 kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; FKSG21; G kinase anchoring protein 1; G kinase-anchoring protein 1; gkap1; GKAP1_HUMAN; GKAP42; Protein kinase anchoring protein GKAP42
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-366
  • 氨基酸序列
    MASAVLSSVP TTASRFALLQ VDSGSGSDSE PGKGKGRNTG KSQTLGSKST TNEKKREKRR KKKEQQQSEA NELRNLAFKK IPQKSSHAVC NAQHDLPLSN PVQKDSREEN WQEWRQRDEQ LTSEMFEADL EKALLLSKLE YEEHKKEYED AENTSTQSKV MNKKDKRKNH QGKDRPLTVS LKDFHSEDHI SKKTEELSSS QTLSHDGGFF NRLEDDVHKI LIREKRREQL TEYNGTDNCT AHEHNQEVVL KDGRIERLKL ELERKDAEIQ KLKNVITQWE AKYKEVKARN AQLLKMLQEG EMKDKAEILL QVDESQSIKN ELTIQVTSLH AALEQERSKV KVLQAELAKY QGGRKGKRNS ESDQCR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
  • 基因功能参考文献：
    1. This paper describes the protein interaction, expression, localization and function of a highly similar gene in mouse. PMID: 10671526
  • 亚细胞定位：
    Golgi apparatus.
  • 蛋白家族：
    GKAP1 family
  • 数据库链接：

    HGNC: 17496

    OMIM: 611356

    KEGG: hsa:80318

    STRING: 9606.ENSP00000365550

    UniGene: Hs.522255