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  4. Recombinant Human Elongator complex protein 6 homolog (C3orf75)

Recombinant Human Elongator complex protein 6 homolog (C3orf75)

  • 货号：
    CSB-YP608122HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP608122HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP608122HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP608122HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP608122HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ELP6
  • Uniprot No.：
  • 别名：
    ELP6; ATP1; C3orf75; TMEM103Elongator complex protein 6; Angiotonin-transactivated protein 1; Protein TMEM103
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-266
  • 氨基酸序列
    MFVELNNLLN TTPDRAEQGK LTLLCDAKTD GSFLVHHFLS FYLKANCKVC FVALIQSFSH YSIVGQKLGV SLTMARERGQ LVFLEGLKSA VDVVFQAQKE PHPLQFLREA NAGNLKPLFE FVREALKPVD SGEARWTYPV LLVDDLSVLL SLGMGAVAVL DFIHYCRATV CWELKGNMVV LVHDSGDAED EENDILLNGL SHQSHLILRA EGLATGFCRD VHGQLRILWR RPSQPAVHRD QSFTYQYKIQ DKSVSFFAKG MSPAVL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Involved in cell migration.
  • 基因功能参考文献：
    1. ELP6 is expressed intracellularly in developing and mature granulocytes and monocytes but not in lymphocytes and erythrocytes. PMID: 24284306
    2. data identify DERP6/ELP5 and C3ORF75/ELP6 as key players for migration, invasion and tumorigenicity of melanoma cells, as integral subunits of Elongator. PMID: 22854966
  • 蛋白家族：
    ELP6 family
  • 数据库链接：

    HGNC: 25976

    OMIM: 615020

    KEGG: hsa:54859

    STRING: 9606.ENSP00000296149

    UniGene: Hs.311100