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  4. Recombinant Human Glycerophosphocholine cholinephosphodiesterase ENPP6 (ENPP6)

Recombinant Human Glycerophosphocholine cholinephosphodiesterase ENPP6 (ENPP6)

  • 货号：
    CSB-YP740915HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP740915HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP740915HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP740915HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP740915HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ENPP6
  • Uniprot No.：
  • 别名：
    ENPP6; UNQ1889/PRO4334Glycerophosphocholine cholinephosphodiesterase ENPP6; GPC-Cpde; EC 3.1.4.-; EC 3.1.4.38; Choline-specific glycerophosphodiester phosphodiesterase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; E-NPP 6; NPP-6
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length of mature protein
  • 表达区域：
    23-419
  • 氨基酸序列
    RRKLLVFL LDGFRSDYIS DEALESLPGF KEIVSRGVKV DYLTPDFPSL SYPNYYTLMT GRHCEVHQMI GNYMWDPTTN KSFDIGVNKD SLMPLWWNGS EPLWVTLTKA KRKVYMYYWP GCEVEILGVR PTYCLEYKNV PTDINFANAV SDALDSFKSG RADLAAIYHE RIDVEGHHYG PASPQRKDAL KAVDTVLKYM TKWIQERGLQ DRLNVIIFSD HGMTDIFWMD KVIELNKYIS LNDLQQVKDR GPVVSLWPAP GKHSEIYNKL STVEHMTVYE KEAIPSRFYY KKGKFVSPLT LVADEGWFIT ENREMLPFWM NSTGRREGWQ RGWHGYDNEL MDMRGIFLAF GPDFKSNFRA APIRSVDVYN VMCNVVGITP LPNNGSWSRV MCMLKGRAS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids.
  • 基因功能参考文献：
    1. NPP6 has a specific role through the hydrolysis of polyunsaturated LPC, glycerophosphorylcholine, or sphingosylphosphorylcholine in kidney and brain PMID: 15788404
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Note=A small amount of the protein may be found in the extracellular milieu.
  • 蛋白家族：
    Nucleotide pyrophosphatase/phosphodiesterase family
  • 组织特异性：
    Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level).
  • 数据库链接：

    HGNC: 23409

    OMIM: 616983

    KEGG: hsa:133121

    STRING: 9606.ENSP00000296741

    UniGene: Hs.297814